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WormBase Tree Display for Gene: WBGene00019079

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Name Class

WBGene00019079SMapS_parentSequenceF59A3
IdentityVersion3
NameCGC_namerpa-4
Sequence_nameF59A3.6
Molecular_name (17)
Other_nameCELE_F59A3.6Accession_evidenceNDBBX284601
Public_namerpa-4
DB_infoDatabaseAceViewgene1G78C
1G78
WormQTLgeneWBGene00019079
WormFluxgeneWBGene00019079
NDBlocus_tagCELE_F59A3.6
PanthergeneCAEEL|EnsemblGenome=WBGene00019079|UniProtKB=P91356
familyPTHR13989
NCBIgene186576
RefSeqproteinNM_001392313.1
NM_001380262.1
NM_001380260.1
NM_001313492.3
NM_001380261.1
NR_132558.1
TrEMBLUniProtAccQ8I7G2
P91356
A0A0K3AU77
UniProt_GCRPUniProtAccP91356
RNAcentralURSidURS0000858321
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:01WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
208 Mar 2010 11:14:55WBPerson2970Name_changeCGC_namerpa-4
313 Nov 2014 14:58:10WBPerson1983EventAcquires_mergeWBGene00019078
Acquires_mergeWBGene00019078
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrpa
AlleleWBVar01282808
WBVar01499786
WBVar00638575
WBVar00638576
WBVar00638577
WBVar00638578
WBVar00251323
WBVar01498959
StrainWBStrain00051041
WBStrain00051033
WBStrain00051036
WBStrain00051034
RNASeq_FPKM (74)
GO_annotation00050747
00050748
00050749
00050750
00050751
00050752
00050753
00050754
Ortholog (28)
ParalogWBGene00019767Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionrpa-4 encodes an ortholog of human replication protein A2 (HGNC:RPA2); rpa-4 appears to be a complexed/merged loci; it would seem that rpa-4 has undergone a partial duplication to create what was previously named rpa-3 (isoforms e/f of the current annotation) but this duplication event did not include any of the promoter/regulatory regions; transcription now appears to start at the 5' end of rpa-4 and continue all the way through to the end of the partial duplicate in a single transcript; there is a possibility that the transcript(s) produced at this loci are processed into a series of isoforms/alternate gene products but this would need to be confirmed in the laboratory.Curator_confirmedWBPerson324
WBPerson1983
Date_last_updated29 Oct 2014 00:00:00
Automated_descriptionPredicted to enable single-stranded DNA binding activity and telomeric DNA binding activity. Predicted to be involved in DNA replication; double-strand break repair via homologous recombination; and nucleotide-excision repair. Predicted to be located in chromosome, telomeric region and site of double-strand break. Predicted to be part of DNA replication factor A complex. Is an ortholog of human RPA2 (replication protein A2) and RPA4 (replication protein A4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF59A3.6a
F59A3.6c
F59A3.6d
F59A3.6e
F59A3.6f
Corresponding_transcriptF59A3.6b
F59A3.6a.1
F59A3.6a.2
F59A3.6a.3
F59A3.6a.4
F59A3.6c.1
F59A3.6d.1
F59A3.6e.1
F59A3.6f.1
Other_sequenceCRC00661_1
CBC05818_1
CR01805
Associated_featureWBsf649171
WBsf219443
Experimental_infoRNAi_resultWBRNAi00003858Inferred_automaticallyRNAi_primary
WBRNAi00049104Inferred_automaticallyRNAi_primary
WBRNAi00049105Inferred_automaticallyRNAi_primary
WBRNAi00003857Inferred_automaticallyRNAi_primary
Expr_patternExpr1013454
Expr1018492
Expr1038240
Expr1152847
Expr1152848
Expr2015416
Expr2033651
Drives_constructWBCnstr00026080
WBCnstr00037828
Construct_productWBCnstr00026080
WBCnstr00037828
Microarray_results (29)
Expression_cluster (81)
Interaction (66)
Map_infoMapIPosition0.072369Error0.006034
PositivePositive_cloneF59A3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00037751
WBPaper00038491
WBPaper00060907
WBPaper00064312
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene