WormBase Tree Display for Gene: WBGene00019104

WBGene00019104 SMap: S_parent: Sequence: F59D6
  Identity: Version: 2
    Name: CGC_name: asp-7 Person_evidence: WBPerson261
      Sequence_name: F59D6.2
      Molecular_name: F59D6.2
        F59D6.2.1
        CE35328
      Other_name: CELE_F59D6.2 Accession_evidence: NDB BX284605
      Public_name: asp-7
    DB_info: Database: AceView gene 5D507
        WormQTL gene WBGene00019104
        WormFlux gene WBGene00019104
        NDB locus_tag CELE_F59D6.2
        Panther gene CAEEL|WormBase=WBGene00019104|UniProtKB=O16339
          family PTHR13683
        NCBI gene 186613
        RefSeq protein NM_071425.3
        TREEFAM TREEFAM_ID TF315800
        TrEMBL UniProtAcc O16339
        UniProt_GCRP UniProtAcc O16339
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 23 Nov 2012 14:10:21 WBPerson2970 Name_change: CGC_name: asp-7
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: asp
    Allele (38)
    RNASeq_FPKM (74)
    GO_annotation: 00027887
      00027888
      00027889
      00124036
      00124037
    Ortholog (61)
    Paralog (17)
    Structured_description: Automated_description: Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in Alzheimer's disease and frontotemporal dementia. Is an ortholog of human BACE1 (beta-secretase 1); BACE2 (beta-secretase 2); and PGC (progastricsin). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:933,HGNC:934)
      DOID:9255 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:934)
  Molecular_info: Corresponding_CDS: F59D6.2
    Corresponding_CDS_history: F59D6.2:wp107
    Corresponding_transcript: F59D6.2.1
  Experimental_info: RNAi_result: WBRNAi00033194 Inferred_automatically: RNAi_primary
      WBRNAi00089096 Inferred_automatically: RNAi_primary
      WBRNAi00016095 Inferred_automatically: RNAi_primary
      WBRNAi00076506 Inferred_automatically: RNAi_primary
      WBRNAi00049175 Inferred_automatically: RNAi_primary
      WBRNAi00102070 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1026615
      Expr1152921
      Expr2009471
      Expr2027709
    Drives_construct: WBCnstr00026062
    Construct_product: WBCnstr00026062
    Microarray_results (17)
    Expression_cluster (76)
    Interaction: WBInteraction000196225
  Map_info: Map: V Position: -12.7959
    Positive: Positive_clone: F59D6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene