WormBase Tree Display for Gene: WBGene00019362
expand all nodes | collapse all nodes | view schema
| WBGene00019362 | SMap | S_parent | Sequence | K03E5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cdk-2 | Person_evidence | WBPerson346 | |||||
| Sequence_name | K03E5.3 | ||||||||
| Molecular_name | K03E5.3a | ||||||||
| K03E5.3a.1 | |||||||||
| CE51951 | |||||||||
| K03E5.3b | |||||||||
| CE33134 | |||||||||
| K03E5.3b.1 | |||||||||
| Other_name | CELE_K03E5.3 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | cdk-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:01 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 15 Jun 2006 12:11:54 | WBPerson2970 | Name_change | CGC_name | cdk-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cdk | ||||||||
| Allele (127) | |||||||||
| Strain | WBStrain00037658 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (41) | |||||||||
| Ortholog (29) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Concise_description | cdk-2 encodes the C. elegans ortholog of cyclin-dependent kinase 2; along with CYE-1 (cyclin E), CDK-2 is required for the G1/S transition in somatic cells, centrosome assembly and polarity establishment in the embryo, proliferation of germ cells, and suppression of terminal differentiation in quiescent cells after asymmetric division; CYE-1 and CDK-2 also regulate the germline mitosis/meiosis decision through post-translational regulation of GLD-1, likely direct phosphorylation. | Paper_evidence | WBPaper00028806 | |||||
| WBPaper00029347 | |||||||||
| WBPaper00038281 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 28 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Involved in several processes, including pseudocleavage; regulation of mitotic cell cycle; and regulation of protein localization. Part of chromatin. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K03E5.3a | |||||||
| K03E5.3b | |||||||||
| Corresponding_CDS_history | K03E5.3:wp258 | ||||||||
| K03E5.3a:wp123 | |||||||||
| K03E5.3a:wp144 | |||||||||
| K03E5.3b:wp144 | |||||||||
| Corresponding_transcript | K03E5.3a.1 | ||||||||
| K03E5.3b.1 | |||||||||
| Other_sequence (14) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern | Expr14517 | ||||||||
| Expr1023248 | |||||||||
| Expr1038367 | |||||||||
| Expr1153546 | |||||||||
| Expr2009810 | |||||||||
| Expr2028051 | |||||||||
| Drives_construct | WBCnstr00025887 | ||||||||
| Construct_product | WBCnstr00025887 | ||||||||
| WBCnstr00041069 | |||||||||
| Regulate_expr_cluster | WBPaper00040426:CYE-1_CDK-2AF_downregulated | ||||||||
| WBPaper00040426:CYE-1_CDK-2AF_upregulated | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (91) | |||||||||
| Interaction | WBInteraction000050893 | ||||||||
| WBInteraction000500801 | |||||||||
| WBInteraction000502905 | |||||||||
| WBInteraction000504783 | |||||||||
| WBInteraction000543024 | |||||||||
| WBInteraction000556584 | |||||||||
| Map_info | Map | I | Position | -3.75027 | Error | 0.015398 | |||
| Positive | Positive_clone | K03E5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (28) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
