WormBase Tree Display for Gene: WBGene00022078
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| WBGene00022078 | SMap | S_parent | Sequence | Y69A2AR | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | epg-9 | Paper_evidence | WBPaper00041409 | |||||
| Person_evidence | WBPerson716 | ||||||||
| Sequence_name | Y69A2AR.7 | ||||||||
| Molecular_name | Y69A2AR.7a | ||||||||
| Y69A2AR.7a.1 | |||||||||
| CE46347 | |||||||||
| Y69A2AR.7b | |||||||||
| CE30472 | |||||||||
| Y69A2AR.7c | |||||||||
| CE33953 | |||||||||
| Y69A2AR.7b.1 | |||||||||
| Y69A2AR.7c.1 | |||||||||
| Other_name | CELE_Y69A2AR.7 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | epg-9 | ||||||||
| DB_info | Database | AceView | gene | 4D371 | |||||
| WormQTL | gene | WBGene00022078 | |||||||
| WormFlux | gene | WBGene00022078 | |||||||
| NDB | locus_tag | CELE_Y69A2AR.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00022078|UniProtKB=Q95XH2 | |||||||
| family | PTHR13292 | ||||||||
| NCBI | gene | 177040 | |||||||
| RefSeq | protein | NM_001028394.5 | |||||||
| NM_171287.6 | |||||||||
| NM_171288.5 | |||||||||
| TREEFAM | TREEFAM_ID | TF320996 | |||||||
| TrEMBL | UniProtAcc | Q95XH2 | |||||||
| Q86DD3 | |||||||||
| H2L0S0 | |||||||||
| UniProt_GCRP | UniProtAcc | Q95XH2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 21 Nov 2012 14:39:04 | WBPerson2970 | Name_change | CGC_name | epg-9 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | epg | ||||||||
| Allele (198) | |||||||||
| Strain | WBStrain00008604 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00023287 | ||||||||
| 00023288 | |||||||||
| 00023289 | |||||||||
| 00023290 | |||||||||
| 00023291 | |||||||||
| 00126261 | |||||||||
| Contained_in_operon | CEOP4658 | ||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | epg-9 encodes the C. elegans homolog of mammalian ATG101 (AuTophaGy101); in C. elegans, epg-9 is required for autophagic degradation of protein aggregates and for normal survival rates under conditions of food deprivation; EPG-9 physically interacts with ATG-13, the C. elegans homolog of ATG13, and UNC-51, the C. elegans homolog of ATG1; an EPG-9::GFP reporter fusion is ubiquitously expressed during embryogenesis and widely expressed in postembryonic stages, including in pharyngeal muscles, neurons and intestinal cells. | Paper_evidence | WBPaper00041409 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 27 Sep 2012 00:00:00 | ||||||||
| Automated_description | Enables protein kinase binding activity. Involved in aggrephagy. Predicted to be located in phagophore assembly site. Expressed in several structures, including body wall musculature; head; hypodermis; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in cholangiocarcinoma; colon cancer; and hepatocellular carcinoma. Is an ortholog of human ATG101 (autophagy related 101). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4947 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:25679) | ||||
| DOID:219 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:25679) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:25679) | ||||||
| Molecular_info | Corresponding_CDS | Y69A2AR.7a | |||||||
| Y69A2AR.7b | |||||||||
| Y69A2AR.7c | |||||||||
| Corresponding_CDS_history | Y69A2AR.7a:wp227 | ||||||||
| Corresponding_transcript | Y69A2AR.7a.1 | ||||||||
| Y69A2AR.7b.1 | |||||||||
| Y69A2AR.7c.1 | |||||||||
| Other_sequence (12) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00058056 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr10545 | ||||||||
| Expr14806 | |||||||||
| Expr1013465 | |||||||||
| Expr1039715 | |||||||||
| Expr1161473 | |||||||||
| Expr2011348 | |||||||||
| Expr2029584 | |||||||||
| Drives_construct | WBCnstr00014931 | ||||||||
| WBCnstr00024350 | |||||||||
| WBCnstr00040925 | |||||||||
| Construct_product | WBCnstr00024350 | ||||||||
| WBCnstr00040925 | |||||||||
| Microarray_results (36) | |||||||||
| Expression_cluster (110) | |||||||||
| Interaction | WBInteraction000518881 | ||||||||
| WBInteraction000522754 | |||||||||
| WBInteraction000522755 | |||||||||
| WBInteraction000522756 | |||||||||
| WBInteraction000522757 | |||||||||
| WBInteraction000518882 | |||||||||
| Map_info | Map | IV | Position | -7.0721 | |||||
| Positive | Positive_clone | Y69A2AR | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00041409 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00056693 | |||||||||
| WBPaper00056814 | |||||||||
| WBPaper00057218 | |||||||||
| WBPaper00061251 | |||||||||
| WBPaper00062416 | |||||||||
| WBPaper00064575 | |||||||||
| WBPaper00065262 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
