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WormBase Tree Display for Gene: WBGene00022152

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Name Class

WBGene00022152SMapS_parentSequenceY71G12B
IdentityVersion3
NameCGC_nameatg-5Person_evidenceWBPerson649
Sequence_nameY71G12B.12
Molecular_nameY71G12B.12a
Y71G12B.12a.1
CE43967
Y71G12B.12b
CE39066
Y71G12B.12c
CE39065
Y71G12B.12b.1
Y71G12B.12c.1
Other_nameatgr-5Person_evidenceWBPerson649
CELE_Y71G12B.12Accession_evidenceNDBBX284601
Public_nameatg-5
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
227 Apr 2006 11:26:11WBPerson2970Name_changeCGC_nameatgr-5
329 Feb 2008 11:29:00WBPerson2970Name_changeCGC_nameatg-5
Other_nameatgr-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classatg
Allele (185)
Possibly_affected_byWBVar02158465
WBVar02158466
RNASeq_FPKM (74)
GO_annotation (17)
Contained_in_operonCEOP1020
Ortholog (34)
Structured_descriptionConcise_descriptionatg-5 encodes, by alternative splicing, two isoforms of an ortholog of the autophagic budding yeast protein Atg5p, and of human ATG5 (OMIM:604261); ATG-5 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00031045
WBPaper00031504
Curator_confirmedWBPerson567
Date_last_updated27 Feb 2008 00:00:00
Automated_descriptionPredicted to contribute to Atg8-family ligase activity. Involved in autophagosome assembly and regulation of autophagy. Predicted to be located in phagophore assembly site membrane. Predicted to be part of Atg12-Atg5-Atg16 complex. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 25. Is an ortholog of human ATG5 (autophagy related 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080259Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:589)
Molecular_infoCorresponding_CDSY71G12B.12a
Y71G12B.12b
Y71G12B.12c
Corresponding_CDS_historyY71G12B.12a:wp147
Y71G12B.12a:wp205
Y71G12B.12b:wp147
Corresponding_transcriptY71G12B.12a.1
Y71G12B.12b.1
Y71G12B.12c.1
Other_sequence (25)
Associated_featureWBsf982742
WBsf982743
WBsf1009244
WBsf1009245
WBsf217240
Experimental_infoRNAi_resultWBRNAi00117121Inferred_automaticallyRNAi_primary
WBRNAi00058198Inferred_automaticallyRNAi_primary
WBRNAi00086922Inferred_automaticallyRNAi_primary
Expr_patternExpr1018812
Expr1039758
Expr1161615
Expr2009494
Expr2027731
Microarray_results (25)
Expression_cluster (65)
Interaction (13)
Map_infoMapIPosition-13.2176Error0.036147
PositivePositive_cloneY71G12BInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene