WormBase Tree Display for Gene: WBGene00022491
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| WBGene00022491 | SMap | S_parent | Sequence | Y119D3B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | Sequence_name | Y119D3B.14 | |||||||
| Molecular_name | Y119D3B.14 | ||||||||
| Y119D3B.14.1 | |||||||||
| CE45193 | |||||||||
| Other_name | CELE_Y119D3B.14 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | Y119D3B.14 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele (207) | |||||||||
| Strain | WBStrain00002757 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP3060 | ||||||||
| Ortholog (36) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Concise_description | Y119D3B.14 encodes the the C. elegans ortholog of mitochondrial translation elongation factor G2 (EFG2), a GTP-binding protein essential for the elongation phase of protein synthesis; loss of Y119D3B.14 activity via RNAi in a wild-type background results in embryonic and larval lethality, sterility, body morphology defects, and slow growth rates. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00012935 | |||||||||
| WBPaper00025054 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Aug 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTPase activity. Predicted to be involved in mitochondrial translation and ribosome disassembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 39. Is an ortholog of human GFM2 (GTP dependent ribosome recycling factor mitochondrial 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111475 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29682) | ||||
| Molecular_info | Corresponding_CDS | Y119D3B.14 | |||||||
| Corresponding_CDS_history | Y119D3B.14:wp216 | ||||||||
| Corresponding_transcript | Y119D3B.14.1 | ||||||||
| Other_sequence (13) | |||||||||
| Associated_feature | WBsf991243 | ||||||||
| WBsf1014187 | |||||||||
| WBsf226185 | |||||||||
| WBsf226186 | |||||||||
| WBsf226187 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00055509 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00020003 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1593 | ||||||||
| Expr6896 | |||||||||
| Expr1016800 | |||||||||
| Expr1039937 | |||||||||
| Expr1159013 | |||||||||
| Expr2007078 | |||||||||
| Expr2025306 | |||||||||
| Drives_construct | WBCnstr00003285 | ||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (78) | |||||||||
| Interaction (44) | |||||||||
| Map_info | Positive | Positive_clone | Y119D3B | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | III | -22.6321 | |||||||
| Reference | WBPaper00012935 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
