WormBase Tree Display for Gene: WBGene00022817
expand all nodes | collapse all nodes | view schema
WBGene00022817 | SMap | S_parent | Sequence | ZK783 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | upp-1 | Person_evidence | WBPerson1855 | |||||
Sequence_name | ZK783.2 | ||||||||
Molecular_name | ZK783.2 | ||||||||
ZK783.2.1 | |||||||||
CE34466 | |||||||||
Other_name | CELE_ZK783.2 | Accession_evidence | NDB | BX284603 | |||||
Public_name | upp-1 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:06 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 27 Mar 2008 16:15:11 | WBPerson2970 | Name_change | CGC_name | upp-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | upp | ||||||||
Allele (39) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (24) | |||||||||
Ortholog (44) | |||||||||
Paralog | WBGene00019199 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
Structured_description | Concise_description | upp-1 encodes the C. elegans uridine phosphorylase ortholog; loss of upp-1 activity results in resistance to the anticancer pyrimidine analog 5-fluorouracil (5-FU); in vitro, UPP-1 exhibits both uridine and thymidine phosphorylase activity. | Paper_evidence | WBPaper00035098 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 14 Aug 2009 00:00:00 | ||||||||
Automated_description | Enables thymidine phosphorylase activity and uridine phosphorylase activity. Involved in thymidine metabolic process; uracil catabolic process; and uridine catabolic process. Predicted to be located in cytosol. Expressed in gonad; hypodermis; pharynx; and spermatheca. Is an ortholog of human UPP1 (uridine phosphorylase 1) and UPP2 (uridine phosphorylase 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | ZK783.2 | |||||||
Corresponding_CDS_history | ZK783.2:wp101 | ||||||||
Corresponding_transcript | ZK783.2.1 | ||||||||
Other_sequence (81) | |||||||||
Associated_feature | WBsf651216 | ||||||||
WBsf976221 | |||||||||
WBsf976222 | |||||||||
WBsf981510 | |||||||||
WBsf993071 | |||||||||
WBsf993072 | |||||||||
WBsf227009 | |||||||||
Experimental_info | RNAi_result | WBRNAi00002145 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00005385 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00081723 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00059711 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00022161 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr8778 | ||||||||
Expr14274 | |||||||||
Expr1021055 | |||||||||
Expr1040096 | |||||||||
Expr1163128 | |||||||||
Expr2017928 | |||||||||
Expr2036064 | |||||||||
Drives_construct | WBCnstr00013516 | ||||||||
WBCnstr00023950 | |||||||||
Construct_product | WBCnstr00023950 | ||||||||
Microarray_results (21) | |||||||||
Expression_cluster (174) | |||||||||
Interaction (32) | |||||||||
Map_info | Map | III | Position | -0.651054 | Error | 0.001723 | |||
Positive | Positive_clone | ZK783 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00030430 | ||||||||
WBPaper00031571 | |||||||||
WBPaper00035098 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00041771 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00061547 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |