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WormBase Tree Display for Gene: WBGene00022817

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Name Class

WBGene00022817SMapS_parentSequenceZK783
IdentityVersion2
NameCGC_nameupp-1Person_evidenceWBPerson1855
Sequence_nameZK783.2
Molecular_nameZK783.2
ZK783.2.1
CE34466
Other_nameCELE_ZK783.2Accession_evidenceNDBBX284603
Public_nameupp-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:06WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
227 Mar 2008 16:15:11WBPerson2970Name_changeCGC_nameupp-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classupp
Allele (39)
RNASeq_FPKM (74)
GO_annotation (24)
Ortholog (44)
ParalogWBGene00019199Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionupp-1 encodes the C. elegans uridine phosphorylase ortholog; loss of upp-1 activity results in resistance to the anticancer pyrimidine analog 5-fluorouracil (5-FU); in vitro, UPP-1 exhibits both uridine and thymidine phosphorylase activity.Paper_evidenceWBPaper00035098
Curator_confirmedWBPerson1843
Date_last_updated14 Aug 2009 00:00:00
Automated_descriptionEnables thymidine phosphorylase activity and uridine phosphorylase activity. Involved in thymidine metabolic process; uracil catabolic process; and uridine catabolic process. Predicted to be located in cytosol. Expressed in gonad; hypodermis; pharynx; and spermatheca. Is an ortholog of human UPP1 (uridine phosphorylase 1) and UPP2 (uridine phosphorylase 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK783.2
Corresponding_CDS_historyZK783.2:wp101
Corresponding_transcriptZK783.2.1
Other_sequence (81)
Associated_featureWBsf651216
WBsf976221
WBsf976222
WBsf981510
WBsf993071
WBsf993072
WBsf227009
Experimental_infoRNAi_resultWBRNAi00002145Inferred_automaticallyRNAi_primary
WBRNAi00005385Inferred_automaticallyRNAi_primary
WBRNAi00081723Inferred_automaticallyRNAi_primary
WBRNAi00059711Inferred_automaticallyRNAi_primary
WBRNAi00022161Inferred_automaticallyRNAi_primary
Expr_patternExpr8778
Expr14274
Expr1021055
Expr1040096
Expr1163128
Expr2017928
Expr2036064
Drives_constructWBCnstr00013516
WBCnstr00023950
Construct_productWBCnstr00023950
Microarray_results (21)
Expression_cluster (174)
Interaction (32)
Map_infoMapIIIPosition-0.651054Error0.001723
PositivePositive_cloneZK783Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00030430
WBPaper00031571
WBPaper00035098
WBPaper00038491
WBPaper00041771
WBPaper00055090
WBPaper00061547
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene