WormBase Tree Display for Gene: WBGene00043705
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| WBGene00043705 | SMap | S_parent | Sequence | Y55F3AM | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | egrh-2 | Person_evidence | WBPerson460 | |||||
| Sequence_name | Y55F3AM.7 | ||||||||
| Molecular_name (18) | |||||||||
| Other_name | CELE_Y55F3AM.7 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | egrh-2 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00043705 | |||||
| WormFlux | gene | WBGene00043705 | |||||||
| NDB | locus_tag | CELE_Y55F3AM.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00043705|UniProtKB=U4PBA8 | |||||||
| family | PTHR23235 | ||||||||
| NCBI | gene | 190308 | |||||||
| RefSeq | protein | NM_001380027.1 | |||||||
| NM_001392252.1 | |||||||||
| NM_001392251.1 | |||||||||
| NM_001307470.3 | |||||||||
| NM_001380026.1 | |||||||||
| NM_001307471.4 | |||||||||
| TrEMBL | UniProtAcc | U4PM44 | |||||||
| U4PBA8 | |||||||||
| U4PBN9 | |||||||||
| A0A7R9SV07 | |||||||||
| U4PEI2 | |||||||||
| A0A7R9SUP3 | |||||||||
| UniProt_GCRP | UniProtAcc | U4PBA8 | |||||||
| OMIM | gene | 129010 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 04 Oct 2004 10:58:10 | WBPerson1971 | Event | Created | |||
| Killed | |||||||||
| 2 | 26 Mar 2007 13:57:19 | WBPerson2970 | Event | Resurrected | |||||
| Name_change | CGC_name | egrh-2 | |||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | egrh | ||||||||
| Allele (112) | |||||||||
| Strain | WBStrain00055457 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00104968 | ||||||||
| 00104969 | |||||||||
| 00104970 | |||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00003480 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00007772 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00009743 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00009998 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00012735 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00018990 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00044651 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | egrh-2 encodes a zinc finger protein that has similarity to the vertebrate EGR (early growth response factor) family of proteins, including the human EGR transcription factors. | Paper_evidence | WBPaper00037082 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 12 Jan 2015 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); lung disease (multiple); and neuropathy (multiple). Is an ortholog of human EGR1 (early growth response 1) and EGR3 (early growth response 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (19) | ||||||||
| Molecular_info | Corresponding_CDS | Y55F3AM.7a | |||||||
| Y55F3AM.7b | |||||||||
| Y55F3AM.7c | |||||||||
| Y55F3AM.7d | |||||||||
| Y55F3AM.7e | |||||||||
| Y55F3AM.7f | |||||||||
| Corresponding_CDS_history | Y55F3AM.7:wp124 | ||||||||
| Y55F3AM.7:wp239 | |||||||||
| Corresponding_transcript | Y55F3AM.7a.1 | ||||||||
| Y55F3AM.7b.1 | |||||||||
| Y55F3AM.7c.1 | |||||||||
| Y55F3AM.7d.1 | |||||||||
| Y55F3AM.7e.1 | |||||||||
| Y55F3AM.7f.1 | |||||||||
| Other_sequence | MPC00438_1 | ||||||||
| MP01432 | |||||||||
| Transcription_factor | WBTranscriptionFactor000519 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00021027 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00057533 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1021685 | ||||||||
| Expr1160967 | |||||||||
| Expr2011235 | |||||||||
| Expr2029471 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (80) | |||||||||
| Map_info | Map | IV | Position | -22.8138 | Error | 0.028363 | |||
| Positive | Positive_clone | Y55F3AM | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027309 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | The corresponding CDS object for this gene had been created and removed before WormBase introduced the concept of unique gene identifiers. This (dead) gene object exists as an attempt to make sure that a gene ID exists for every worm gene prediction that has ever existed. | Curator_confirmed | WBPerson1971 | ||||||
| A modified version of this gene was resurrected based on C.briggsae homology and twinscan data. | Curator_confirmed | WBPerson1867 | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
