WormBase Tree Display for Gene: WBGene00044508
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| WBGene00044508 | SMap | S_parent | Sequence | C18F3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | nsy-7 | Person_evidence | WBPerson42 | |||||
| Sequence_name | C18F3.4 | ||||||||
| Molecular_name | C18F3.4a | ||||||||
| C18F3.4a.1 | |||||||||
| CE42065 | |||||||||
| C18F3.4b | |||||||||
| CE49558 | |||||||||
| C18F3.4b.1 | |||||||||
| Other_name | CELE_C18F3.4 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | nsy-7 | ||||||||
| DB_info | Database | AceView | gene | 4I848 | |||||
| WormFlux | gene | WBGene00044508 | |||||||
| NDB | locus_tag | CELE_C18F3.4 | |||||||
| NCBI | gene | 3896760 | |||||||
| RefSeq | protein | NM_001268381.4 | |||||||
| NM_001268380.2 | |||||||||
| SwissProt | UniProtAcc | H2KYW5 | |||||||
| TREEFAM | TREEFAM_ID | TF343693 | |||||||
| UniProt_GCRP | UniProtAcc | H2KYW5 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 14 Jun 2005 09:36:29 | WBPerson1867 | Event | Created | |||
| 2 | 02 Mar 2009 16:14:50 | WBPerson9133 | Name_change | CGC_name | nsy-7 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nsy | ||||||||
| Allele (43) | |||||||||
| Strain | WBStrain00040551 | ||||||||
| WBStrain00040552 | |||||||||
| WBStrain00040564 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00021947 | ||||||||
| 00021948 | |||||||||
| 00021949 | |||||||||
| 00021950 | |||||||||
| 00021951 | |||||||||
| 00021952 | |||||||||
| 00021953 | |||||||||
| Ortholog (25) | |||||||||
| Structured_description | Concise_description | nsy-7 encodes a protein with distant similarity to homeodomain transcription factors; during neuronal development, nsy-7 functions downstream of an initial embryonic signaling pathway involving unc-2, unc-36, and nsy-1, to coordinate the transition from initial establishment to subsequent stable specification (maintenance) of the AWC-ON cell fate; in regulating the AWC-ON fate, NSY-7 likely acts as a transcriptional regulator that represses expression of AWC-OFF genes, such as srsx-3 and hlh-11, in the AWC-ON cell; in vitro, NSY-7 displays sequence-specific, DNA-binding activity to elements found within the promoter regions of srsx-3 and hlh-11; consistent with its role as a transcriptional regulator, a NSY-7::GFP reporter localizes to the AWC nucleus; nsy-7::gfp promoter fusions are expressed in gut, the amphid sheath glial cells, and head and tail neurons including AWC, ASE, and ASH. | Paper_evidence | WBPaper00032896 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 29 May 2009 00:00:00 | ||||||||
| Automated_description | Enables sequence-specific DNA binding activity. Involved in determination of left/right asymmetry in nervous system and negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in amphid sheath cell; intestine; and neurons. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C18F3.4a | |||||||
| C18F3.4b | |||||||||
| Corresponding_CDS_history | C18F3.4:wp187 | ||||||||
| C18F3.4b:wp241 | |||||||||
| Corresponding_transcript | C18F3.4a.1 | ||||||||
| C18F3.4b.1 | |||||||||
| Other_sequence (13) | |||||||||
| Associated_feature (15) | |||||||||
| Gene_product_binds | WBsf047507 | ||||||||
| WBsf047508 | |||||||||
| Transcription_factor | WBTranscriptionFactor000090 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00107915 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr8537 | ||||||||
| Expr8538 | |||||||||
| Expr15633 | |||||||||
| Expr15716 | |||||||||
| Expr1010369 | |||||||||
| Expr1040274 | |||||||||
| Expr1145010 | |||||||||
| Expr2014508 | |||||||||
| Expr2032747 | |||||||||
| Drives_construct | WBCnstr00013351 | ||||||||
| WBCnstr00013352 | |||||||||
| WBCnstr00023514 | |||||||||
| WBCnstr00042413 | |||||||||
| WBCnstr00042490 | |||||||||
| Construct_product | WBCnstr00013352 | ||||||||
| WBCnstr00023514 | |||||||||
| WBCnstr00042413 | |||||||||
| Microarray_results (13) | |||||||||
| Expression_cluster (87) | |||||||||
| Interaction | WBInteraction000532447 | ||||||||
| WBInteraction000544544 | |||||||||
| WBInteraction000544574 | |||||||||
| WBInteraction000544608 | |||||||||
| WBInteraction000560250 | |||||||||
| WBInteraction000565328 | |||||||||
| Anatomy_function | WBbtf0559 | ||||||||
| Map_info | Map | IV | Position | 3.59693 | Error | 0.002199 | |||
| Positive | Positive_clone | C18F3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Pos_neg_data | 10957 | |||||||
| 10958 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00032896 | ||||||||
| WBPaper00058960 | |||||||||
| WBPaper00060123 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
