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WormBase Tree Display for Gene: WBGene00044630

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Name Class

WBGene00044630SMapS_parentSequenceCHROMOSOME_X
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classbus
Reference_alleleWBVar00145005
Allele (196)
StrainWBStrain00004675
WBStrain00004761
WBStrain00004698
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (31)
Paralog (18)
Structured_descriptionConcise_descriptionbus-17 encodes a putative GT13 glycosyltransferase whose homologs include human B3GALT2 and C. elegans BRE-5; BUS-17 is required for bacterial infection, as well as for cuticle integrity, long-term survival, and traction during movement; specifically, bus-17 is needed both for colonization by Microbacterium nematophilum (and the tail-swelling response to M. nematophilum infection) and for attachment of Yersinia pseudotuberculosis biofilms; bus-17 is also needed for normal cuticle antigens; BUS-17 is predicted to have an N-terminal signal sequence and a moderately conserved active site; bus-17 and bus-3 function together in vivo, since bus-17(e2695)/+ sometimes shows nonallelic noncomplementation with bus-3(e2696)/+; bus-17 males are sometimes wild-type if their fathers were wild-type.Paper_evidenceWBPaper00026735
WBPaper00028877
WBPaper00029153
WBPaper00030782
Curator_confirmedWBPerson567
Date_last_updated17 Jul 2007 00:00:00
Automated_descriptionPredicted to enable UDP-glycosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in membrane. Is an ortholog of human B3GALT1 (beta-1,3-galactosyltransferase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK678.8
Corresponding_CDS_historyZK678.8:wp165
Corresponding_transcriptZK678.8.1
Other_sequence (14)
Associated_featureWBsf654672
WBsf238352
Experimental_infoExpr_patternExpr1018042
Expr1040292
Expr1163070
Expr2009684
Expr2027923
Drives_constructWBCnstr00023433
Construct_productWBCnstr00023433
Microarray_results (13)
Expression_cluster (131)
WBProcessWBbiopr:00000039
Map_info (3)
Reference (15)
MethodGene