WormBase Tree Display for Interaction: WBInteraction000501549
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WBInteraction000501549 | Interaction_type | Regulatory | |
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Interactor (2) | |||
Interaction_summary | The expression pattern of the LIN-11::GFP translational fusion construct (plin-11-ABCDE::GFP, which does not include the LIN-11 homeobox domain) was examined. This construct is expressed in wild-type animals both in the nucleus and in the cytoplasm of the {pi} cells and vulval cells. In the smo-1(ok359) uterus, the {pi} cells are not normally differentiated. The intensity of the LIN-11::GFP transgene in smo-1(ok359) was much weaker and diffused compared with the wild-type pattern (early L4 n = 23/26) and could be detected with high variability only in a few uterine cells (one to four cells in each side of the uterus, compared with six cells in the wild type). In a few cases the transgene was not expressed at all in the uterus (n = 3/26). Moreover, whereas in the wild-type developing uterus the {pi} cells migrate after dividing, in the smo-1(ok359) animals the LIN-11::GFP-expressing cells were clustered and failed to occupy the correct stereotypic positions. | ||
Detection_method | Reporter_gene | [lin-11::gfp] translational fusion. | |
Paper | WBPaper00024467 |