WormBase Tree Display for Interaction: WBInteraction000501648
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| WBInteraction000501648 | Interaction_type | Regulatory | |||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001250 | Interactor_type | Trans_regulator | |
| WBGene00001649 | Interactor_type | Trans_regulated | |||
| Interaction_summary | The expression of five general intestinal genes, including GATA-regulated genes (ges-1, ifb-2) and genes that contribute to intestine structure development and maintenance (let-413, eps-8, and gob-1), was largely not affected by elt-2 knockdown. | ||||
| Detection_method | RT_PCR | quantitative RT-PCR | |||
| Paper | WBPaper00028482 | ||||
| Remark | Furthermore, knocking down the expression of gob-1 did not affect susceptibility to PA14. Together, these results indicate that elt-2 knockdown in adult animals increases susceptibility to infection not through the impairment of general intestinal function but through its specific role in regulating immunity genes. |
