WormBase Tree Display for Interaction: WBInteraction000502751
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| WBInteraction000502751 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003006 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr4251 | ||||
| Transgene | WBTransgene00000991 | ||||
| Construct | WBCnstr00000983 | ||||
| WBGene00003029 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00090265 | Interactor_type | Trans_regulator | ||
| Interaction_summary | Prior to division, LIN-17::GFP accumulated asymmetrically to the anterior cortex and cytoplasm of the B cell in 81% of males (n = 31). After division, LIN-17::GFP was symmetrically localized within the B.a cell cortex, but was asymmetrically localized within the B.p cell in 76% (n = 33) of males, with the anterior membrane and cytoplasm displaying a higher level of LIN-17::GFP than the posterior. LIN-17::GFP was localized symmetrically in 73% (n = 30) of lin-44 males before the B cell division and was symmetrically localized in 81% (n = 52) after division. However, while LIN-17::GFP was symmetrically localized within the B.a and B.p membranes, distribution of LIN-17::GFP to the B.a and B.p cells was reversed in 23% of lin-44 males, with the B.p cell membrane having a higher level than B.a, was equally distributed in 58% and was normally distributed in 19% (n = 52) of lin-44 males. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [lin-17::gfp], translational fusion | ||||
| Transgene | |||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0003825 | ||
| Subcellular_localization | LIN-17::GFP accumulated asymmetrically to the anterior cortex and cytoplasm of the B cell. | ||||
| Paper | WBPaper00028965 |
