WormBase Tree Display for Interaction: WBInteraction000518625
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WBInteraction000518625 | Interaction_type | Regulatory | Change_of_expression_level | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00004267 | Interactor_type | Trans_regulated | |
Transgene | WBTransgene00006556 | ||||
Construct | WBCnstr00006403 | ||||
WBGene00012644 | Interactor_type | Trans_regulator | |||
Variation_interactor | WBVar00250504 | Interactor_type | Trans_regulator | ||
Interaction_summary | Both SNB-1::GFP and RAB-3::mCherry exhibited significantly increased intensity in synaptic puncta of rabx-5 mutants, and RAB-3::mCherry had increased intensity in intersynaptic regions as well. SNB-1::GFP intensity was significantly increased in cell bodies, whereas RAB-3::mCherry intensity was significantly decreased. Thus, while there are differential effects in cell somas, synaptic vesicles appear to be increased in synaptic regions of rabx-5 mutants. | ||||
Detection_method | Construct | ||||
Reporter_gene | [rab-3::mCherry] | ||||
Transgene | |||||
Regulation_level | Post_translational | ||||
Regulation_result | Positive_regulate | Anatomy_term | WBbt:0005190 | ||
Subcellular_localization | synapses | ||||
Unaffiliated_expr_pattern | Expr3544 | ||||
Paper | WBPaper00041164 |