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WormBase Tree Display for Interaction: WBInteraction000518625

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Name Class

WBInteraction000518625Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00004267Interactor_typeTrans_regulated
TransgeneWBTransgene00006556
ConstructWBCnstr00006403
WBGene00012644Interactor_typeTrans_regulator
Variation_interactorWBVar00250504Interactor_typeTrans_regulator
Interaction_summaryBoth SNB-1::GFP and RAB-3::mCherry exhibited significantly increased intensity in synaptic puncta of rabx-5 mutants, and RAB-3::mCherry had increased intensity in intersynaptic regions as well. SNB-1::GFP intensity was significantly increased in cell bodies, whereas RAB-3::mCherry intensity was significantly decreased. Thus, while there are differential effects in cell somas, synaptic vesicles appear to be increased in synaptic regions of rabx-5 mutants.
Detection_methodConstruct
Reporter_gene[rab-3::mCherry]
Transgene
Regulation_levelPost_translational
Regulation_resultPositive_regulateAnatomy_termWBbt:0005190
Subcellular_localizationsynapses
Unaffiliated_expr_patternExpr3544
PaperWBPaper00041164