WormBase Tree Display for Interaction: WBInteraction000524184
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| WBInteraction000524184 | Interaction_type | Genetic | Enhancement | ||
|---|---|---|---|---|---|
| GI_module_two | Enhancing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00001510 | Interactor_type | Effector | |
| WBGene00003161 | Interactor_type | Affected | |||
| Variation_interactor | WBVar00091675 | Interactor_type | Effector | ||
| WBVar00251124 | Interactor_type | Affected | |||
| Interaction_summary | fzr-1; mdf-2 double mutants revealed that they have significantly reduced brood sizes (~11 progeny per worm) and significantly reduced numbers of fertile adults (~50% of all adult progeny are fertile), resulting in only two or three fertile adult progeny per hermaphrodite compared to about 10 to 15 fertile adults produced by mdf-2 homozygotes. Furthermore, we observed that while mdf-2 homozygotes displayed CIN as determined by high incidence of males (Him) phenotype (~3% of the adult progeny are males; n = 252), fzr-1 increases this chromosome instability to ~6% (n = 107 adult progeny observed). | ||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0000688 | ||||
| WBPhenotype:0000154 | |||||
| WBPhenotype:0001175 | |||||
| Paper | WBPaper00037616 |
