WormBase Tree Display for Interaction: WBInteraction000535989

WBInteraction000535989 Interaction_type: Genetic: Mutual_enhancement
    GI_module_one: Cis_phenotypic
    GI_module_two: Enhancing
    GI_module_three: Diverging
  Interactor: Interactor_overlapping_gene: WBGene00006868 Interactor_type: Non_directional
      WBGene00003111 Interactor_type: Non_directional
    Variation_interactor: WBVar00143310 Interactor_type: Non_directional
      WBVar00142901 Interactor_type: Non_directional
  Interaction_summary: vab-1(e2) and mab-20(ev574) mutually enhance each others P cell misalignment phenotype (Table S2). "However, the few P cell alignment defects of the vab-1 kinase dead mutant are enhanced additively by plx-2 and synergistically by mab-20 null mutations, whereas the alignment defects of the vab-1 null are enhanced largely additively by the plx-2 null (Figure 5A). These results suggest that the kinase and nonkinase functions of VAB-1 act in a molecular pathway that functions largely in parallel with the PLX-2 pathway, whereas VAB-1 acts redundantly with MAB-20 to regulate P cell alignment."
  Throughput: Low_throughput
  Interaction_phenotype: WBPhenotype:0001118
  Paper: WBPaper00040551
  Remark: Table S2, Figure 5A