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WormBase Tree Display for Interaction: WBInteraction000541867

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Name Class

WBInteraction000541867Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00004204Interactor_typeTrans_regulator
WBGene00002090Interactor_typeTrans_regulated
Interaction_summary"We used transcriptional reporters of two DAF-16/FOXO-regulated genes, sod-3 and ins-7, to examine DAF-16/FOXO-dependent transcriptional activation and repression, respectively[6,20]. Expression of the Psod-3::GFP reporter is induced under conditions of low insulin-like signalling, for example, in daf-2 mutants[18]... repression of Pins-7::ins-7::GFP was suppressed by RNAi against SWI/SNF subunits, in particular SWSN-4 and SWSN-1 and to a lesser extent SWSN-8, SWSN-3 and SNFC-5 (Fig. 2c,d)."
Detection_methodReporter_gene[INS7::gfp]
Regulation_resultNegative_regulateLife_stageWBls:0000067
PaperWBPaper00042296
RemarkFig. 2cd