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WormBase Tree Display for Interaction: WBInteraction000554745

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Name Class

WBInteraction000554745Interaction_typePhysicalProteinProtein
InteractorInteractor_overlapping_geneWBGene00000912Interactor_typeBait
WBGene00010923Interactor_typeTarget
Interaction_summaryRLE-1 was detected by coimmunoprecipitation and western blotting when it was coexpressed with DAF-16 but not in the control lane of RLE-1 alone.
RLE-1 was detected in the anti-DAF-16 immunoprecipitate when lysates of wild-type worms but not of rle-1 mutants were used.
RLE-1 colocalizes with DAF-16 in C. elegans as demonstrated by confocal microscopy.
Deletion of the C terminus of RLE-1 completely abolished its interaction with DAF-16, indicating the RLE-1 C terminus is required for the interaction of RLE-1 with DAF-16.
Detection_methodAffinity_capture_Western
ThroughputLow_throughput
WBProcessWBbiopr:00000001
DB_infoDatabaseBioGRIDInteraction ID555975
PaperWBPaper00029081