WormBase Tree Display for Interaction: WBInteraction000569505
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WBInteraction000569505 | Interaction_type | Genetic | Mutual_suppression | ||
---|---|---|---|---|---|
GI_module_one | Trans_phenotypic | ||||
GI_module_two | Suppressing | ||||
Interactor | Interactor_overlapping_gene | WBGene00004202 | Interactor_type | Non_directional | |
WBGene00006925 | Interactor_type | Non_directional | |||
WBGene00006926 | Interactor_type | Non_directional | |||
Variation_interactor | WBVar00089203 | Interactor_type | Non_directional | ||
Interaction_summary | "We also examined the lifespan phenotype following vit-1/2 RNAi and observed a marked rescue of the lifespan defect (Mallick et al. 2020) in pry-1(mu38) (102% increase in mean lifespan). The wildtype animals showed a comparatively lower increase in the mean lifespan (16.6%) (Figures 1F and 1G). Overall, these findings show that vit-2 functions downstream of pry-1 to regulate both lipid levels and lifespan." | ||||
Throughput | Low_throughput | ||||
Interaction_RNAi | WBRNAi00114748 | ||||
WBRNAi00114749 | |||||
Interaction_phenotype | WBPhenotype:0000039 | ||||
Paper | WBPaper00059995 | ||||
Remark | Figure 1F, 1G |