WormBase Tree Display for Picture: WBPicture0000007640

WBPicture0000007640 Description: Figure 6. FRK-1 is expressed ubiquitously in all cells during embryogenesis, and becomes nuclear excluded just before enclosure. FRK-1 is localized to the nucleus and at regions of cell-cell contacts in early embryos, as evident in 4-cell (A) and 40-cell (B) embryos. Immediately before enclosure, FRK-1 becomes nuclear-excluded, as seen in an embryo with approximately 550 cells (C). The protein remains nuclear-excluded throughout elongation (e.g. 1.25-fold stage; D), and cell surface localization is especially pronounced in the seam cells of elongated embryos (e.g. 3-fold embryo, E; overlay with MH27 apical junction antigen in F). Arrows point to apical junctions surrounding seam cells. Although both antibodies result in the same staining pattern, the images in this figure show localization using the antibody elicited to the FRK-1b peptide (see Materials and methods).
  Name: F6.large.jpg
  Depict: Expr_pattern: Expr3701
    Anatomy: WBbt:0004017
    Cellular_component: GO:0005634
      GO:0005737
      GO:0005886
      GO:0005911
  Acknowledgment: Template: WormBase thanks <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>.
    Publication_year: 2005
    Article_URL: DOI id 10.1242/dev.01900
    Journal_URL: Development
    Publisher_URL: TheCompanyofBiologists
  Reference: WBPaper00026609