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WBPicture0000008931 Description: Figure 2. Expression patterns of cle-1::GFP transcriptional reporters. Isoform-specific GFP transcriptional reporters show the expression patterns of cle-1A (A and E), cle-1B (B and F), and cle-1C (C, D, G, and H). In A-D, anterior is up and dorsal is to the left; in E-H, anterior is to the left, and dorsal is up. (A) cle-1A expression in the cephalic neurons of a 1.75-fold stage embryo. Expression is also seen in S-type interneurons at later stages. (B) cle-1B expression in a threefold embryo is seen in DD ventral motorneurons (four are visible and two are out of the plane of focus). This GFP fusion localizes to the nucleus, making axon visualization difficult. (C) cle-1C expression in the body wall muscles (bm) of a twofold embryo. Pharyngeal expression is not seen in this focal plane. (D) In a threefold embryo, cle-1C expression in body wall muscles is weaker, but strong expression is seen in pharyngeal cells (p), accessory muscles, some unidentified cells near the anus (a), and the canal-associated neurons (CAN). (E) In an L2 larva, cle-1A expression is strong in the nerve ring (nr) and rectal epithelial cells (re). GFP is weakly detected in axons of the S-type interneurons that run sublaterally. (F) cle-1B expression in dorsal motorneuron cell bodies (arrowheads) located along the ventral nerve cord of an L2 larva. Faint GFP activity can be detected in commissural axons of most animals. (G) cle-1C expression in an L2 larva is limited to a subset of glial-like GLR cells, the head mesodermal cell (hm), the canal-associated neurons, and weakly in the anal sphincter muscle (sm). (H) cle-1C expression in adult body wall muscles (bm), accessory muscles (sm), canal associated neurons (CAN), and gonadal sheath cells (sc).
  Name: F2.large.jpg
  Depict: Expr_pattern: Expr859
    Anatomy (11)
  Acknowledgment: Template: WormBase thanks <Journal_URL> for permission to reproduce figures from this article. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>. The user must not use the Work for commercial purposes. If the user shares, alters, transforms, or builds upon the Work, the user may distribute the resulting work only under the same license the user received from <Publisher_URL>.
    Publication_year: 2001
    Article_URL: DOI id 10.1083/jcb.152.6.1219
    Journal_URL: TheJournalofCellBiology
    Publisher_URL: TheRockefellerUniversityPress
  Reference: WBPaper00004615