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WBPicture0000009023DescriptionFigure 1. ARL-13/Arl13b is enriched in proximal regions of ciliary axonemes. (A) ARL-13::GFP localizes almost exclusively to the proximal region (MSs; m) of amphid/phasmid cilia and male tail ray cilia. Although localizing to all regions of AWB cilia, ARL-13 is enriched in proximal regions and observed at the membrane of distal fans (arrow). IFT markers (CHE-2 and -11) label amphid/phasmid channel MSs and DSs (d) and RnA/B male tail ray cilia. Kymographs, from time-lapse videos, show no IFT movement for ARL-13::GFP. Arrowheads indicate RnA/B cilia, and insets show high magnification images of RnA/B cilia. (B) Arl13b is enriched in the proximal region of MDCKII cilia. Images after immunostaining for endogenous Arl13b, acetylated alpha-tubulin (ciliary axoneme), and gamma-tubulin (basal body) are shown. Bars: (A, left and right) 3 um; (A, middle) 10 um; (A, insets) 1 um; (B) 5 um.
NameF1.large.jpg
DepictExpr_patternExpr8950
AnatomyWBbt:0006816
Cellular_componentGO:0097730
AcknowledgmentTemplateWormBase thanks <Journal_URL> for permission to reproduce figures from this article. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>. The user must not use the Work for commercial purposes. If the user shares, alters, transforms, or builds upon the Work, the user may distribute the resulting work only under the same license the user received from <Publisher_URL>.
Publication_year2010
Article_URLDOIid10.1083/jcb.200908133
Journal_URLTheJournalofCellBiology
Publisher_URLTheRockefellerUniversityPress
ReferenceWBPaper00036031