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WBPicture0000009652DescriptionFigure 3. CAM-1 Is Expressed in Both Neurons and Muscles. (A) Schematic diagram of a worm. (B) Confocal image of head region (boxed area in [A]) from a transgenic worm that expressed CAM-1::GFP. Indicated are the nerve ring (blue arrowhead), neuronal cell bodies (white arrowhead), and ventral nerve cord (arrow). (C) Confocal images of a transgenic L4 worm expressing CAM-1::YFP (red, upper) and unc-4::CFP (green, middle); merged image, lower. (D) Confocal images of the ventral nerve cord of a transgenic adult worm expressing CAM-1::YFP (red, top) and acr-2::SNB-1::CFP (middle, green); merged image, bottom. Arrowheads denote areas of punctate fluorescence. CAM-1 and SNB-1 were colocalized at most puncta (white arrowheads). However, SNB-1 puncta without accompanying CAM-1 puncta (blue arrowheads) and CAM-1 puncta without accompanying SNB-1 puncta (purple arrowhead) were infrequently observed. (E) Schematic diagram of a worm showing the region (box) represented in the confocal image of a transgenic worm expressing CAM-1::GFP (F). The worm has been rolled 90 degrees from the position depicted in (A) to visualize the ventral nerve cord and NMJ regions more clearly. Intense CAM-1::GFP fluorescence (arrows) is observed at the distal extent of muscle arms at points of contact with the ventral nerve cord (mu, muscle; v, vulva). The red line in (A) and (E) represents the ventral nerve cord.
NameF3.jpg
DepictExpr_patternExpr3509
AnatomyWBbt:0005829
WBbt:0006749
Cellular_componentGO:0031594
GO:0043005
GO:0043025
AcknowledgmentTemplateReprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>.
Publication_year2005
Article_URLDOIid10.1016/j.neuron.2005.04.010
Journal_URLNeuron
Publisher_URLElsevier
ReferenceWBPaper00025245