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| WBPicture0000011157 | Description | Figure 5. Dauers remodel the expression of DAF-6 Patched. a, Photomicrographs of GFP-tagged DAF-6 protein (DAF-6::GFP) in WT animals. DAF-6::GFP was observed in the sheath and socket cells in L4 larvae. In dauers, DAF-6::GFP expression in the sheath and socket cells was dramatically reduced but colocalized with the dauer alae. All animals shown have anterior toward the left. b, Expression of DAF-6::GFP in the sheath and socket cells was progressively restored when WT animals recovered from the dauer stage. The definitions of GFP levels are as follows: strong, WT L4 levels as shown in the left panel of a; weak, fluorescence in characteristic sheath and socket cells can be identified; none, the characteristic structure of these cells cannot be recognized. The numbers shown are from a single experiment, with 30-40 animals assayed for each time point. Experiments repeated on independent days show similar relative differences. | |||
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| Name | F5.large.jpg | ||||
| Depict | Expr_pattern | Expr8603 | |||
| Anatomy | WBbt:0005750 | ||||
| WBbt:0005811 | |||||
| Acknowledgment | Template | WormBase thanks <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>. | |||
| Publication_year | 2009 | ||||
| Article_URL | DOI | id | 10.1523/JNEUROSCI.0044-09.2009 | ||
| Journal_URL | TheJournalofNeuroscience | ||||
| Publisher_URL | SocietyofNeuroscience | ||||
| Reference | WBPaper00033037 |
