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WormBase Tree Display for Picture: WBPicture0000012426

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WBPicture0000012426Description(B) cpx-1 is expressed in the nervous system. Top: gene model and regions deleted in C. elegans complexin mutant alleles (red bars). The black line represents the region of the genome used to create the rescuing GFP construct. Gray triangle on transcript represents the 3'UTR. GFP was inserted after the first three codons. Bottom: a reporter construct consisting of the cpx-1 gene with GFP inserted at the N terminus of complexin is expressed in many neurons in the head and body of the animal. Neurons expressing cpx-1 include the motor neurons of the ventral nerve cord, neurons in the head ganglia, and also neurons of the pharyngeal nervous system, including the MC and M4 motorneurons. The inset shows the punctate localization of GFP::CPX-1 along the dorsal nerve cord. Confocal images were taken of young adult hermaphrodites oriented dorsal up and anterior to the left. Images are a stitch of multiple confocal Z projections along the length of the animal.
NameFigA_A.jpg
CropCropped_fromWBPicture0000012425
DepictExpr_patternExpr9229
AnatomyWBbt:0005735
AcknowledgmentTemplateReprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>.
Publication_year2011
Article_URLDOIid10.1016/j.cub.2010.12.015
Journal_URLCurrentBiology
Publisher_URLElsevier
ReferenceWBPaper00037990