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WBPicture0000014293Description(D-G) Expression of the pfk-1.1 promoter is observed in neurons of the ventral and dorsal nerve cords (arrows) (D); and in head neurons, including the NSM neurons (E-G).(H) Schematic of the glycolysis pathway and mutants examined in this study. Enzymes are shown in black, while substrates are in blue. Numbers inside parentheses indicate the number of identified C. elegans homologs for each given enzyme in the pathway. Solid red arrow denotes enzymatic reactions in the glycolysis pathway. Dashed arrows denote regulatory steps: (+) for activation and (-) for inhibition. Asterisk marks genes examined in this study. We selected the specific enzymes for analyses based on availability of identified alleles from the Caenorhabditis Genomic Center (CGC). With the exception of 6-phosphofructokinase/pfk-1.1, which was identified in our forward genetic screen, all other enzymes were selected based on theavailability of deletion alleles. Scale bar represents 25um for (D), and 5um for (E). Error bars denote SEM. *, p < 0.05. **, p <0.01. ***, p < 0.001 between indicated groups.
NameFigS2_A.jpg
CropCropped_fromWBPicture0000014292
DepictExpr_patternExpr12930
AnatomyWBbt:0003679
WBbt:0004446
WBbt:0004457
Cellular_componentGO:0043005
GO:0043025
AcknowledgmentTemplateReprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>.
Publication_year2016
Article_URLDOIid10.1016/j.neuron.2016.03.011
Journal_URLNeuron
Publisher_URLElsevier
ReferenceWBPaper00049486