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WBPicture0000014527DescriptionFigure 2. MOAG-2/LIR-3 Preferentially Binds to Promoters of Small ncRNAs (A) Subcellular localization of MOAG-2/LIR-3 in wild-type N2 worms. Scale bar, 50 mm. Arrowheads point at nuclei; asterisk is non-specific staining. See alsoFigure S2A.(B) Enrichment of binding of MOAG-2/LIR-3 to different gene biotypes (1 kb upstream/downstream of TSS) relative to genes distributed genome-wide. See alsoFigure S2B.(C) MOAG-2/LIR-3 binding sites within 1,000 and +1,000 bp of TSS for protein-coding, ncRNA, tRNA, and snoRNA genes.(D) Enriched consensus DNA motifs for MOAG-2/LIR-3 with p value.(E) Number of MOAG-2/LIR-3 binding sites containing Box A and Box B.(F) Heatmap showing the binding of different transcription factors to C. elegans promoters of protein-coding, snoRNA, and tRNA genes. The hierarchicalclustering was generated using the average linkage cluster method with a binary metric distance.
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CropCrop_pictureWBPicture0000014528
AcknowledgmentTemplateReprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>.
Publication_year2017
Article_URLDOIid10.1016/j.molcel.2017.02.022
Journal_URLMolecularCell
Publisher_URLElsevier
ReferenceWBPaper00050937