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WBPicture0000014656DescriptionS1 Fig. HPK-1 spatial expression during development and subcellularlocalization.(A) HPK-1 is broadly expressed during development, with limited expression byadulthood. (A, Top left) Expression of Phpk-1::HPK-1::GFP during embryogenesis. (A,top right) Phpk-1::HPK-1::GFP expression becomes increasingly restricted by the L3stage of development to neurons (arrow with N), intestinal cells (arrow with I), and thehypodermis (arrow with H). (A bottom panel) HPK-1 expression is limited to neuronalcells by the L4 stage of development and in adults (not shown). Brightfield insets foreach image and white dotted lines trace animals. In all cases, representative images areshown of at least fifteen animals from two independently derived lines. (B) HPK-1 islocalized in the nucleus. Phpk-1::HPK-1::GFP expression with the overlay of DIC image.Arrows indicate examples of localized expression within nuclei.
NameFigS1.jpg
DepictExpr_patternExpr13561
AnatomyWBbt:0003679
WBbt:0004017
WBbt:0005409
WBbt:0005753
WBbt:0005772
WBbt:0006751
Cellular_componentGO:0005634
AcknowledgmentTemplateReprinted from <Journal_URL>, <Article_URL>. <Publisher_URL> <Publication_year>.
Publication_year2017
Article_URLDOIid10.1371/journal.pgen.1007038
Journal_URLPLoSGenetics
Publisher_URLPLoS
ReferenceWBPaper00053206