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| WBPicture0000014893 | Description | Figure 6. DEX-1 is localized to the outer ridges of the lateral alae. (A) Functional781 full-length dex-1p::sfgfp::dex-1 and truncated dex-1p::dex-1(ecto)::sfgfp constructs782 rescue the dex-1(ns42) SDS sensitivity phenotype to wild-type levels. Error bars, 95%783 confidence interval. Non-overlapping confidence intervals were considered significantly784 different (*) (n=60 per genotype pooled from three independent trials). (B) Lateral view785 overlay (top), fluorescence (middle), and DIC (bottom) micrograph of a dex-1(ns42)786 dauer expressing a full length dex-1p::sfgfp::dex-1 construct. The full length dex787 1p::sfgfp::dex-1 construct rescues the lateral alae phenotype in a mosaic pattern. dex788 1::sfgfp::dex-1 localizes in a diffuse pattern to the areas immediately below the outer789 ridges of rescued, intact lateral alae (arrowhead). In contrast, in areas where lateral alae790 are not rescued, DEX-1 expression is bright and punctate and localizes throughout the791 lateral ridge (arrow). Scale bar, 10um. | |||
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| Name | Fig6.jpg | ||||
| Crop | Crop_picture | WBPicture0000014894 | |||
| Acknowledgment | Template | WormBase thanks the journal <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Journal_URL>, <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL> | |||
| Publication_year | 2018 | ||||
| Article_URL | DOI | id | 10.1534/genetics.118.301557 | ||
| Journal_URL | Genetics | ||||
| Publisher_URL | GSA | ||||
| Reference | WBPaper00055641 |
