WormBase Tree Display for RNAi: WBRNAi00077564

WBRNAi00077564 Homol: Homol_homol: R12B2:RNAi
  Sequence_info: PCR_product: sjj_R12B2.5
  Experiment: Laboratory: KRY
    Date: 10 Jan 2008 00:00:00
    Strain: WBStrain00004828
    Treatment: L1 animals transfered to RNAi in the presence of various concentrations of toxins, and monitored their development and morphology until day four of adulthood.
    Delivered_by: Bacterial_feeding
  Inhibits: Predicted_gene: R12B2.5b Inferred_automatically: RNAi_primary
      R12B2.5a Inferred_automatically: RNAi_primary
    Gene: WBGene00007016 Inferred_automatically: RNAi_primary
    Transcript: R12B2.5a.2 Inferred_automatically: RNAi_primary
      R12B2.5b.2 Inferred_automatically: RNAi_primary
      R12B2.5a.1 Inferred_automatically: RNAi_primary
      R12B2.5b.1 Inferred_automatically: RNAi_primary
      R12B2.5a.3 Inferred_automatically: RNAi_primary
  Species: Caenorhabditis elegans
  Reference: WBPaper00031850
  Phenotype: WBPhenotype:0001379 Remark: MDT-15 depletion enhances toxin sensitivity. Fluoranthene synergized with mdt-15 RNAi to evoke an arrest as small, scrawny. In contrast, this was not the case for b-naphthoflavone (data not shown).Authors conclude that compromised detoxification capability as a result of reduced MDT-15 function causes growth defects in worms challenged with select toxic compounds.
  Method: RNAi