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WormBase Tree Display for RNAi: WBRNAi00090362

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Name Class

WBRNAi00090362HomolHomol_homolC50H2:RNAi
Sequence_infoPCR_productsjj_C50H2.2
ExperimentLaboratoryCC
Date15 Aug 2011 00:00:00
GenotypeccIs55 [unc-54::lacZ]; unc-51(e369)
Delivered_byBacterial_feeding
InhibitsPredicted_geneC50H2.2aInferred_automaticallyRNAi_primary
C50H2.2bInferred_automaticallyRNAi_primary
GeneWBGene00001211Inferred_automaticallyRNAi_primary
TranscriptC50H2.2b.1Inferred_automaticallyRNAi_primary
C50H2.2a.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000519691
ReferenceWBPaper00040284
Phenotype_not_observedWBPhenotype:0001645RemarkThe unc-51(e369) mutation suppressed the RNAi-induced increase in protein degradation in muscle, as determined by LacZ staining, suggesting that the unc-51 signaling pathway (Autophagy pathway) is responsible for mediating the RNAi-induced increase in protein degradation in muscle.
Remark(Figure 4) egl-47 RNAi
MethodRNAi