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WormBase Tree Display for RNAi: WBRNAi00090367

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Name Class

WBRNAi00090367HomolHomol_homolC50C3:RNAi
Sequence_infoPCR_productsjj_C50C3.9
ExperimentLaboratoryCC
Date15 Aug 2011 00:00:00
GenotypeccIs55 [unc-54::lacZ]; unc-51(e369)
Delivered_byBacterial_feeding
InhibitsPredicted_geneC50C3.9cInferred_automaticallyRNAi_primary
C50C3.9aInferred_automaticallyRNAi_primary
C50C3.9bInferred_automaticallyRNAi_primary
GeneWBGene00006772Inferred_automaticallyRNAi_primary
TranscriptC50C3.9a.1Inferred_automaticallyRNAi_primary
C50C3.9c.1Inferred_automaticallyRNAi_primary
C50C3.9b.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000519696
ReferenceWBPaper00040284
Phenotype_not_observedWBPhenotype:0001645RemarkThe unc-51(e369) mutation suppressed the RNAi-induced increase in protein degradation in muscle, as determined by LacZ staining, suggesting that the unc-51 signaling pathway (Autophagy pathway) is responsible for mediating the RNAi-induced increase in protein degradation in muscle.
Remark(Figure 4) unc-36 RNAi
MethodRNAi