WormBase Tree Display for RNAi: WBRNAi00090804

WBRNAi00090804 Homol: Homol_homol: R11A5:RNAi
  Sequence_info: DNA_text: gttaagcccgtgtcgttgtaagatgactggaattgttgttagacgagttgttgctcacgcgaatcgtcgataaaattgaatcgagccgctcgacttttgtcatcaggtctttgacgattcgattgatgcaagcaccggcgcccgtaccggtagatactcgttggctctgaaagctatgtaaatgttggctgagaactataaatgggttagcaaatattgttttttcggtctattctgcatctagagatgctatcgtttatagttgtgagggaaaaaagaattagaactcgctgcaagagtttttcgactaaatgtttttcattccgaaataaggtgtgaagctattaattgatcgaaatttgcaggtcttctttgaattaatatttggatatttactttcaaaaatccaccaaaaaaagaaaatttacgtactttttcttgaatatttttattgtcatcgatgcgcacttcgtcaatttttgcaatagtttcctccattcgaacatcttcgtggtgctgcacgtcttccatgaaaacatcttccgagccttaaatagtactagttattttcattctcaaaatgcgacaaatacttactcattttaaactcttctttacttggacctggggatggctcgtccggcagaatttctggatcattcctcaatggttctacaatcaaacgtggccgttctgttgttcgaagttgttcttctcgtaatctatgcatttcttcagcagcaacttgccgttcataaagctcactttccaacattgctatcttttcaatagcatgatccagtttcgatccgagatcagatgctagatattccttatttctttctgatgtttcgagcacatcgtttctctgttccagttttcgaattctttctctctgactttcacattgttcatgaagatgtgagttttctcgtcttaattgctcttcgacttgtgcaaattgtacacgggaatcgtcctgtcgatc
  Experiment: Laboratory: MZE
    Date: 19 Apr 2012 00:00:00
    Genotype: unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
    Treatment: Animals were fed dsRNA-expressing bacteria from the L1 stage of the P0 generation; F1 young adult animals were imaged and scored for phenotypes
    Delivered_by: Bacterial_feeding
  Inhibits: Predicted_gene: R11A5.2 Inferred_automatically: RNAi_primary
    Gene: WBGene00011230 Inferred_automatically: RNAi_primary
    Transcript: R11A5.2.1 Inferred_automatically: RNAi_primary
  Species: Caenorhabditis elegans
  Interaction: WBInteraction000519813
  Reference: WBPaper00041129
  Phenotype: WBPhenotype:0000679 Remark: PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; PEPT-1::DsRED fluorescence intensity reduced; PEPT-1::DsRed can be retained in misplaced RAB-11-recycling endosomes (REs); GFP::RAB-11 recycling endosomes (REs) localise basally; GFP::RAB-11 recycling endosomes (REs) distribute evenly or scatter throughout the cell; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated
    WBPhenotype:0001278 Remark: PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; PEPT-1::DsRED fluorescence intensity reduced; PEPT-1::DsRed can be retained in misplaced RAB-11-recycling endosomes (REs); GFP::RAB-11 recycling endosomes (REs) localise basally; GFP::RAB-11 recycling endosomes (REs) distribute evenly or scatter throughout the cell; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated
    WBPhenotype:0002094 Remark: PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; PEPT-1::DsRED fluorescence intensity reduced; PEPT-1::DsRed can be retained in misplaced RAB-11-recycling endosomes (REs); GFP::RAB-11 recycling endosomes (REs) localise basally; GFP::RAB-11 recycling endosomes (REs) distribute evenly or scatter throughout the cell; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated
    WBPhenotype:0002095 Remark: PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; PEPT-1::DsRED fluorescence intensity reduced; PEPT-1::DsRed can be retained in misplaced RAB-11-recycling endosomes (REs); GFP::RAB-11 recycling endosomes (REs) localise basally; GFP::RAB-11 recycling endosomes (REs) distribute evenly or scatter throughout the cell; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated
    WBPhenotype:0002107 Remark: PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; PEPT-1::DsRED fluorescence intensity reduced; PEPT-1::DsRed can be retained in misplaced RAB-11-recycling endosomes (REs); GFP::RAB-11 recycling endosomes (REs) localise basally; GFP::RAB-11 recycling endosomes (REs) distribute evenly or scatter throughout the cell; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated
  Remark: (Table S1, S3) R11A5.2/nud-2 RNAi
  Method: RNAi