WormBase Tree Display for RNAi: WBRNAi00102245
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| WBRNAi00102245 | Homol | Homol_homol | K06A1:RNAi | ||
|---|---|---|---|---|---|
| Sequence_info | PCR_product | sjj_K06A1.5 | |||
| Experiment | Laboratory | GR | |||
| Date | 13 Jan 2013 00:00:00 | ||||
| Temperature | 20 | ||||
| Delivered_by | Bacterial_feeding | ||||
| Inhibits | Predicted_gene | K06A1.5 | Inferred_automatically | RNAi_primary | |
| Gene | WBGene00019427 | Inferred_automatically | RNAi_primary | ||
| Transcript | K06A1.5.1 | Inferred_automatically | RNAi_primary | ||
| Species | Caenorhabditis elegans | ||||
| Reference | WBPaper00041973 | ||||
| Phenotype | WBPhenotype:0000039 | Remark | atg-16.2 is necessary for the LIPL-4 overexpression induced increased lifespan as RNAi decreases the lifespan extention. Other core autophagy genes (bec-1 and lgg-1) are also required for the LIPL-4Ox-driven lifespan phenotype. Overexpression of LIPL-4 promotes starvation survival. In this experiment the ges-1 promoter is used to overexpress LIPL-4 (called LIPL-4Ox). | ||
| Remark | Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. | ||||
| Method | RNAi |
