Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for RNAi: WBRNAi00108056

expand all nodes | collapse all nodes | view schema

Name Class

WBRNAi00108056HomolHomol_homolT07A9:RNAi
Sequence_infoPCR_productsjj_T07A9.6
ExperimentGenotypedaf-2(e1370); daf-16::gfp
Delivered_byBacterial_feeding
InhibitsPredicted_geneT07A9.6Inferred_automaticallyRNAi_primary
GeneWBGene00000913Inferred_automaticallyRNAi_primary
TranscriptT07A9.6.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000536020
ReferenceWBPaper00038374
PhenotypeWBPhenotype:0000679Remark"We therefore asked whether PDP-1 modulates DAF-16 subcellular localization as well as activity (Figure 3A and Figure S8). daf- 2(e1370); daf-16::gfp worms were grown on vector, daf-18 and pdp-1 RNAi, and DAF-16 nuclear/cytosolic localization was visualized using fluorescence microscopy and quantified. Throughout the body of the worm, while DAF-16::GFP was mostly nuclear on vector RNAi, its localization was enriched in the cytosol on pdp-1 RNAi, similar to daf-18 RNAi (Figure 3A and Figure S8)."
Remark(Figure 3A, S8A) daf-18 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
MethodRNAi