WormBase Tree Display for RNAi: WBRNAi00110238
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| WBRNAi00110238 | Homol | Homol_homol | ZC376:RNAi | |||
|---|---|---|---|---|---|---|
| Sequence_info | PCR_product | sjj_ZC376.7 | ||||
| Experiment | Genotype | zcIs13 [hsp-6p::GFP]; rmIs101 [rgef-1p::Q40::YFP] | ||||
| Delivered_by | Bacterial_feeding | |||||
| Inhibits | Predicted_gene | ZC376.7d | Inferred_automatically | RNAi_primary | ||
| ZC376.7b | Inferred_automatically | RNAi_primary | ||||
| ZC376.7a | Inferred_automatically | RNAi_primary | ||||
| ZC376.7c | Inferred_automatically | RNAi_primary | ||||
| Gene | WBGene00013878 | Inferred_automatically | RNAi_primary | |||
| Transcript | ZC376.7d.1 | Inferred_automatically | RNAi_primary | |||
| ZC376.7c.1 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7a.2 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7b.2 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7a.1 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7c.2 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7b.1 | Inferred_automatically | RNAi_primary | ||||
| Species | Caenorhabditis elegans | |||||
| Interaction | WBInteraction000537547 | |||||
| WBInteraction000537552 | ||||||
| Reference | WBPaper00050142 | |||||
| Phenotype | WBPhenotype:0001278 | Remark | "We predicted that the cell-non-autonomous induction of mitochondrial chaperones observed with neuronal polyQ40 expression requires one or more essential UPRmt factors. To test this hypothesis, we applied RNAi against ubl-5, dve-1, atfs-1, and clpp-1, and cco-1 to neuronal polyQ40 worms expressing hsp-6p::GFP. RNAi against dve-1, atfs-1, and clpp-1 blocked the induction of the hsp-6p::GFP reporter in peripheral tissues, while cco-1 RNAi showed robust induction (Figures 2A and 2B)." | |||
| EQ_annotations | GO_term | GO:0034514 | PATO:0000460 | |||
| Remark | (Figure 2A, 2B) atfs-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. | |||||
| Method | RNAi |
