WormBase Tree Display for RNAi: WBRNAi00114543
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WBRNAi00114543 | Homol | Homol_homol | M01B12:RNAi | ||
---|---|---|---|---|---|
Sequence_info | PCR_product | mv_M01B12.5 | |||
Inhibits | Predicted_gene | M01B12.5a | Inferred_automatically | RNAi_primary | |
Gene | WBGene00019698 | Inferred_automatically | RNAi_primary | ||
Transcript | M01B12.5b | Inferred_automatically | RNAi_primary | ||
M01B12.5a.1 | Inferred_automatically | RNAi_primary | |||
M01B12.5a.2 | Inferred_automatically | RNAi_primary | |||
Species | Caenorhabditis elegans | ||||
Reference | WBPaper00046459 | ||||
Phenotype | WBPhenotype:0000688 | Remark | From Text: "Worms in which riok-1 was knocked down displayed an oogenesis-specific sterility that was associated with several defects in gonad organisation. When riok-1 was knocked down, the number of proliferating mitotic cells was significantly reduced, and the nuclei of germ cells entering the diplotene stage of meiosis prophase I had abnormally organised and large nuclei. In the proximal gonad, oocyte maturation appeared abnormal, and oocytes underwent multiple rounds of DNA replication, resulting in the generation of endomitotic oocytes" | ||
Remark | riok-1 (WBGene00019698) RNAi (ORFeome library RNAi clone) | ||||
Method | RNAi |