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WormBase Tree Display for RNAi: WBRNAi00114543

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Name Class

WBRNAi00114543HomolHomol_homolM01B12:RNAi
Sequence_infoPCR_productmv_M01B12.5
InhibitsPredicted_geneM01B12.5aInferred_automaticallyRNAi_primary
GeneWBGene00019698Inferred_automaticallyRNAi_primary
TranscriptM01B12.5bInferred_automaticallyRNAi_primary
M01B12.5a.1Inferred_automaticallyRNAi_primary
M01B12.5a.2Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00046459
PhenotypeWBPhenotype:0000688RemarkFrom Text: "Worms in which riok-1 was knocked down displayed an oogenesis-specific sterility that was associated with several defects in gonad organisation. When riok-1 was knocked down, the number of proliferating mitotic cells was significantly reduced, and the nuclei of germ cells entering the diplotene stage of meiosis prophase I had abnormally organised and large nuclei. In the proximal gonad, oocyte maturation appeared abnormal, and oocytes underwent multiple rounds of DNA replication, resulting in the generation of endomitotic oocytes"
Remarkriok-1 (WBGene00019698) RNAi (ORFeome library RNAi clone)
MethodRNAi