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WormBase Tree Display for Strain: WBStrain00047284

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Name Class

WBStrain00047284StatusLive
Genotypesod-1(tm776) II; rtSi8 IV; him-5 V; vsIs48.
Public_nameHA2464
ContainsGeneWBGene00001864
WBGene00004930
VariationWBVar00249804
WBVar02157389
TransgeneWBTransgene00004893
PropertiesOutcrossedx4
MutagenMosSCI
CGC_received31 Jan 2020 00:00:00
LocationCGC
RemarkMade_by: Saba BaskoyluCGC_data_submission
rtSi8 [sod-1p::sod-1(A4V) + Cbr-unc-119(+)] (inserted into cxTi10882) IV. vsIs48 [unc-17::GFP]. A4V mutation in C. elegans sod-1 genomic rescue construct mimics human SOD1 disease model. Superficially wild-type with increased sensitivity to paraquat in multiple assays. GFP expressed in all cholinergic neurons. Strain reportedly carries a him-5 mutation in the background, though specific allele has not been confirmed. HA2619 serves as a control strain for HA2464. Reference: Baskoylu SN, et al. PLoS Genet. 2018;14(10):e1007682.Inferred_automaticallyFrom CGC strain data
no longer available from the CGC.
SpeciesCaenorhabditis elegans