WormBase Tree Display for Strain: WBStrain00047284
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WBStrain00047284 | Status | Live | ||
---|---|---|---|---|
Genotype | sod-1(tm776) II; rtSi8 IV; him-5 V; vsIs48. | |||
Public_name | HA2464 | |||
Contains | Gene | WBGene00001864 | ||
WBGene00004930 | ||||
Variation | WBVar00249804 | |||
WBVar02157389 | ||||
Transgene | WBTransgene00004893 | |||
Properties | Outcrossed | x4 | ||
Mutagen | MosSCI | |||
CGC_received | 31 Jan 2020 00:00:00 | |||
Location | CGC | |||
Remark | Made_by: Saba Baskoylu | CGC_data_submission | ||
rtSi8 [sod-1p::sod-1(A4V) + Cbr-unc-119(+)] (inserted into cxTi10882) IV. vsIs48 [unc-17::GFP]. A4V mutation in C. elegans sod-1 genomic rescue construct mimics human SOD1 disease model. Superficially wild-type with increased sensitivity to paraquat in multiple assays. GFP expressed in all cholinergic neurons. Strain reportedly carries a him-5 mutation in the background, though specific allele has not been confirmed. HA2619 serves as a control strain for HA2464. Reference: Baskoylu SN, et al. PLoS Genet. 2018;14(10):e1007682. | Inferred_automatically | From CGC strain data | ||
no longer available from the CGC. | ||||
Species | Caenorhabditis elegans |