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WormBase Tree Display for Strain: WBStrain00048126

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Name Class

WBStrain00048126StatusLive
GenotypeoyEx676 [ser-2(2)p::FRT::STOP::FRT::unc-103(gf)::SL2::gfp + odr-2b(3a)p::nFLP + elt-7p::gfp]
Public_namePY12216
ContainsTransgeneWBTransgene00027248
PropertiesPhenotypeWBPhenotype:0002513Paper_evidenceWBPaper00060853
Curator_confirmedWBPerson712
RemarkChronic silencing of AIZ via expression of an activated UNC-103 potassium channel [unc-103(gf)] (Reiner et al., 2006) in this neuron significantly decreased NT regardless of feeding conditions(Figure 1B)Paper_evidenceWBPaper00060853
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000999Paper_evidenceWBPaper00060853
Curator_confirmedWBPerson712
RemarkWe found that starved animals in which AWC has been chronically silenced via expression of unc-103(gf) or genetic ablation (Beverly et al., 2011; Chelur and Chalfie, 2007), continued to exhibit starvation-dependent plasticity in NT similar to the behavioral phenotype of wild-type animals (Figure 1C), but in stark contrast to the behavior of animals in which AWC is acutely silenced (Takeishi et al., 2020).Paper_evidenceWBPaper00060853
Curator_confirmedWBPerson712
LocationPY
Remark[2021-01-13T05:06:59.454Z WBPerson712] New Strain: 10.17912/micropub.biology.000355 WBPaper00060853 oyEx676 [ser-2(2)p::FRT::STOP::FRT::unc-103(gf)::SL2::gfp + odr-2b(3a)p::nFLP + elt-7p::gfp]Curator_confirmedWBPerson712
ReferenceWBPaper00060853
SpeciesCaenorhabditis elegans