Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Transgene: WBTransgene00000018

expand all nodes | collapse all nodes | view schema

Name Class

WBTransgene00000018Public_nameakEx162
Summary[Ppha-4::VAV-1::GFP, Punc-122::GFP]
ConstructionConstructWBCnstr00000018
Coinjection_otherPunc-122::gfp
Genetic_informationExtrachromosomal
PhenotypeWBPhenotype:0000154Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
RemarkPhenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41.Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Caused_by_geneWBGene00006887Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Phenotype_assayTreatmentSingle L4 hermaphrodites transferred to new plates every 12 hours for four days. Minimum of 20 animals were scored.Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Genotypevav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP]Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
WBPhenotype:0000246Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
RemarkPhenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41. More severe phenotype when akEx406 used to rescue ak41, possibly because Ppha-4 expressed at low levels in intestinal cells (see paper for reference).Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Caused_by_geneWBGene00006887Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Phenotype_assayTreatmentDal Santo et. al., Cell 98, 757-767, 1999.Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Genotypevav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP]Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
WBPhenotype:0000666Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
RemarkPhenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41.Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Caused_by_geneWBGene00006887Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Phenotype_assayGenotypevav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP]Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
WBPhenotype:0000668Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
RemarkPhenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41.Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
PenetranceLowPaper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Caused_by_geneWBGene00006887Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Phenotype_assayGenotypevav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP]Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
WBPhenotype:0001200Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
RemarkPhenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41.Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Caused_by_geneWBGene00006887Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Phenotype_assayGenotypevav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP]Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Phenotype_not_observedWBPhenotype:0000545Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
RemarkPhenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41.Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Caused_by_geneWBGene00006887Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Phenotype_assayGenotypevav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP]Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
WBPhenotype:0000643Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Caused_by_geneWBGene00006887Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Phenotype_assayGenotypevav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP]Paper_evidenceWBPaper00026850
Curator_confirmedWBPerson48
Used_forInteractorWBInteraction000052166
WBInteraction000052167
WBInteraction000052169
ReferenceWBPaper00026850
SpeciesCaenorhabditis elegans