WormBase Tree Display for Transgene: WBTransgene00000018
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WBTransgene00000018 | Public_name | akEx162 | |||||||
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Summary | [Ppha-4::VAV-1::GFP, Punc-122::GFP] | ||||||||
Construction | Construct | WBCnstr00000018 | |||||||
Coinjection_other | Punc-122::gfp | ||||||||
Genetic_information | Extrachromosomal | ||||||||
Phenotype | WBPhenotype:0000154 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Remark | Phenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41. | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Caused_by_gene | WBGene00006887 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00026850 | ||||
Curator_confirmed | WBPerson48 | ||||||||
Phenotype_assay | Treatment | Single L4 hermaphrodites transferred to new plates every 12 hours for four days. Minimum of 20 animals were scored. | Paper_evidence | WBPaper00026850 | |||||
Curator_confirmed | WBPerson48 | ||||||||
Genotype | vav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP] | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPhenotype:0000246 | Paper_evidence | WBPaper00026850 | |||||||
Curator_confirmed | WBPerson48 | ||||||||
Remark | Phenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41. More severe phenotype when akEx406 used to rescue ak41, possibly because Ppha-4 expressed at low levels in intestinal cells (see paper for reference). | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Caused_by_gene | WBGene00006887 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00026850 | ||||
Curator_confirmed | WBPerson48 | ||||||||
Phenotype_assay | Treatment | Dal Santo et. al., Cell 98, 757-767, 1999. | Paper_evidence | WBPaper00026850 | |||||
Curator_confirmed | WBPerson48 | ||||||||
Genotype | vav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP] | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPhenotype:0000666 | Paper_evidence | WBPaper00026850 | |||||||
Curator_confirmed | WBPerson48 | ||||||||
Remark | Phenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41. | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Caused_by_gene | WBGene00006887 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00026850 | ||||
Curator_confirmed | WBPerson48 | ||||||||
Phenotype_assay | Genotype | vav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP] | Paper_evidence | WBPaper00026850 | |||||
Curator_confirmed | WBPerson48 | ||||||||
WBPhenotype:0000668 | Paper_evidence | WBPaper00026850 | |||||||
Curator_confirmed | WBPerson48 | ||||||||
Remark | Phenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41. | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Penetrance | Low | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Caused_by_gene | WBGene00006887 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00026850 | ||||
Curator_confirmed | WBPerson48 | ||||||||
Phenotype_assay | Genotype | vav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP] | Paper_evidence | WBPaper00026850 | |||||
Curator_confirmed | WBPerson48 | ||||||||
WBPhenotype:0001200 | Paper_evidence | WBPaper00026850 | |||||||
Curator_confirmed | WBPerson48 | ||||||||
Remark | Phenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41. | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Caused_by_gene | WBGene00006887 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00026850 | ||||
Curator_confirmed | WBPerson48 | ||||||||
Phenotype_assay | Genotype | vav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP] | Paper_evidence | WBPaper00026850 | |||||
Curator_confirmed | WBPerson48 | ||||||||
Phenotype_not_observed | WBPhenotype:0000545 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Remark | Phenotype attributed to ak41 rather than overexpression of the transgene; transgene rescues larval lethality due to disrupted pharyngeal pumping conferred by ak41. | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Caused_by_gene | WBGene00006887 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00026850 | ||||
Curator_confirmed | WBPerson48 | ||||||||
Phenotype_assay | Genotype | vav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP] | Paper_evidence | WBPaper00026850 | |||||
Curator_confirmed | WBPerson48 | ||||||||
WBPhenotype:0000643 | Paper_evidence | WBPaper00026850 | |||||||
Curator_confirmed | WBPerson48 | ||||||||
Caused_by_gene | WBGene00006887 | Paper_evidence | WBPaper00026850 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
Phenotype_assay | Genotype | vav-1(ak41);[Ppha-4::VAV-1::GFP,Punc-122::GFP] | Paper_evidence | WBPaper00026850 | |||||
Curator_confirmed | WBPerson48 | ||||||||
Used_for | Interactor | WBInteraction000052166 | |||||||
WBInteraction000052167 | |||||||||
WBInteraction000052169 | |||||||||
Reference | WBPaper00026850 | ||||||||
Species | Caenorhabditis elegans |