WormBase Tree Display for Transgene: WBTransgene00006063

WBTransgene00006063 Public_name: tvIs42
  Summary: [??::IFB-1K460R::GFP;rol-6]
  Construction: Construct: WBCnstr00005924
  Genetic_information: Integrated
    Phenotype: WBPhenotype:0000436 Paper_evidence: WBPaper00035491
        Curator_confirmed: WBPerson2021
        Remark: K460R protein exhibits a reduced cytoplasmic pool of IFB-1 compared to control Paper_evidence: WBPaper00035491
            Curator_confirmed: WBPerson2021
        Caused_by_gene: WBGene00002053 Paper_evidence: WBPaper00035491
            Curator_confirmed: WBPerson2021
      WBPhenotype:0001409 Paper_evidence: WBPaper00035491
        Curator_confirmed: WBPerson2021
        Remark: Ectopic IFB-1 cytoplasmic filamentous structures and cytoplasmic inclusions Paper_evidence: WBPaper00035491
            Curator_confirmed: WBPerson2021
        Caused_by_gene: WBGene00002053 Paper_evidence: WBPaper00035491
            Curator_confirmed: WBPerson2021
      WBPhenotype:0001864 Paper_evidence: WBPaper00035491
        Curator_confirmed: WBPerson2021
        Remark: The exchange rate between soluble and incorporated IFB-1 subunits was slower in IFB-1 K460R::GFP animals than in control animals Paper_evidence: WBPaper00035491
            Curator_confirmed: WBPerson2021
        Caused_by_gene: WBGene00002053 Paper_evidence: WBPaper00035491
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: FRAP analysis Paper_evidence: WBPaper00035491
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00035491
  Species: Caenorhabditis elegans