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WormBase Tree Display for Transgene: WBTransgene00007118

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Name Class

WBTransgene00007118Public_nameWBPaper00036348Ex2
Summary[rgef-1p::raga-1(DN)]
ConstructionConstructWBCnstr00006943
Construction_summaryThis construct results in pan-neuronal (rgef-1) expressed dominant negative (DN) RAG protein, due to a T18N mutation resulting in constitutive GDP-binding. Transgenic worms bearing extra chromosomal arrays were generated with DNA at concentrations from 5-10 ng/l using standard techniques. Transgenic constructs were coinjected with either Pofm-1::GFP or Pmyo-3::mCherry as a marker. (Schreiber et al., 2010).
Genetic_informationExtrachromosomal
Phenotype_not_observedWBPhenotype:0000039Paper_evidenceWBPaper00036348
Curator_confirmedWBPerson2021
RemarkNo substantial effects on lifespanPaper_evidenceWBPaper00036348
Curator_confirmedWBPerson2021
Caused_by_geneWBGene00006414Paper_evidenceWBPaper00036348
Curator_confirmedWBPerson2021
Associated_withStrainWBStrain00042436
ReferenceWBPaper00036348
SpeciesCaenorhabditis elegans