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WormBase Tree Display for Transgene: WBTransgene00007122

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Name Class

WBTransgene00007122Public_nameWBPaper00036348Ex6
Summary[lag-2p::raga-1(DN)]
ConstructionConstructWBCnstr00006947
Construction_summaryThis construct results in distal tip cell (lag-2) expressed dominant negative (DN) RAG protein due to a T18N mutation resulting in constitutive GDP-binding. Transgenic worms bearing extra chromosomal arrays were generated with DNA at concentrations from 510 ng/l using standard techniques. Transgenic constructs were coinjected with either Pofm-1::GFP or Pmyo-3::mCherry as a marker. (Schreiber et al., 2010).
Genetic_informationExtrachromosomal
Phenotype_not_observedWBPhenotype:0000039Paper_evidenceWBPaper00036348
Curator_confirmedWBPerson2021
RemarkNo substantial effects on lifespanPaper_evidenceWBPaper00036348
Curator_confirmedWBPerson2021
Caused_by_geneWBGene00006414Paper_evidenceWBPaper00036348
Curator_confirmedWBPerson2021
Associated_withStrainWBStrain00042440
ReferenceWBPaper00036348
SpeciesCaenorhabditis elegans