WormBase Tree Display for Transgene: WBTransgene00020251
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| WBTransgene00020251 | Public_name | uthIs248 | ||||||
|---|---|---|---|---|---|---|---|---|
| Summary | [Paak-2::aak-2 genomic(aa 1-321)::GFP::unc-54 3'UTR, Pmyo-2::tdTOMATO] | |||||||
| Construction | Construct | WBCnstr00019723 | ||||||
| Coinjection | WBCnstr00019724 | |||||||
| Genetic_information | Integrated | |||||||
| Phenotype | WBPhenotype:0000006 | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| Remark | "CA-AAK-2 reduces reproductive capacity (Fig 1C)" | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| Caused_by_gene | WBGene00020142 | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| WBPhenotype:0000061 | Paper_evidence | WBPaper00046499 | ||||||
| Curator_confirmed | WBPerson38423 | |||||||
| Remark | "CA-AAK-2 increases C. elegans lifespan (Fig 1A)" | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| Caused_by_gene | WBGene00020142 | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| WBPhenotype:0000231 | Paper_evidence | WBPaper00046499 | ||||||
| Curator_confirmed | WBPerson38423 | |||||||
| Remark | "CA-AAK-2 induces small body size (Fig 1B)" | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| Caused_by_gene | WBGene00020142 | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| WBPhenotype:0000295 | Paper_evidence | WBPaper00046499 | ||||||
| Curator_confirmed | WBPerson38423 | |||||||
| Remark | "C. elegans expressing CA-AAK-2 show a 125% increase in median survival at 33C compared to the wild-type animals (Fig 1G)" | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| Caused_by_gene | WBGene00020142 | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| Phenotype_assay | Treatment | animals exposed to heat stress at 33C. n = 60-100 worms. p < 10^-5 via Log-rank (Mantel-Cox) analysis. | Paper_evidence | WBPaper00046499 | ||||
| Curator_confirmed | WBPerson38423 | |||||||
| Temperature | 33 | Paper_evidence | WBPaper00046499 | |||||
| Curator_confirmed | WBPerson38423 | |||||||
| Associated_with | Strain | WBStrain00040333 | ||||||
| Reference | WBPaper00045844 | |||||||
| WBPaper00046499 | ||||||||
| WBPaper00049290 | ||||||||
| WBPaper00049364 | ||||||||
| WBPaper00049436 | ||||||||
| WBPaper00051304 | ||||||||
| WBPaper00053297 | ||||||||
| WBPaper00054891 | ||||||||
| WBPaper00055177 | ||||||||
| WBPaper00060779 | ||||||||
| Species | Caenorhabditis elegans |
