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WormBase Tree Display for WBProcess: WBbiopr:00000050

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Name Class

WBbiopr:00000050Public_nameResponse to toxicity
SummaryExposure to a toxic substance can activate any number of processes that result in a change in state or activity of the organism. As a soil dwelling organism, C. elegans has evolved defenses against damaging substances in the soil environment and as such has proved to be an ideal organism for studying biological responses to toxins. These responses can occur at an organism level, such as invoking an avoidance behavior, or on a cellular level, such as activation of a cellular stress response. Cellular defenses have been shown to be invoked in response to reactive oxygen species, heavy metals, and toxin-induced unfolded proteins.
Other_nameDetoxification
Response to xenobiotics
Related_topicSpecialisation_ofWBbiopr:00000052
Generalisation_ofWBbiopr:00000096
Involved_entityGeneWBGene00002004Paper_evidenceWBPaper00040384
WBGene00002016Paper_evidenceWBPaper00040384
WBGene00003474Paper_evidenceWBPaper00040384
WBGene00003970Paper_evidenceWBPaper00032255
WBGene00000467Paper_evidenceWBPaper00040384
WBGene00002015Paper_evidenceWBPaper00040384
WBGene00000912Paper_evidenceWBPaper00040384
WBGene00003473Paper_evidenceWBPaper00040384
WBGene00002026Paper_evidenceWBPaper00040384
WBGene00006959Paper_evidenceWBPaper00032255
InteractionWBInteraction000540051
Molecule (23)
Associated_withGO_termGO:0009636
ReferenceWBPaper00032255
WBPaper00035662
WBPaper00040384
WBPaper00041663
WBPaper00046622
WBPaper00060082