WormBase Tree Display for DO_term: DOID:12858
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| DOID:12858 | Name | Huntington's disease | |||
|---|---|---|---|---|---|
| Status | Valid | ||||
| Definition | A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities. | ||||
| Synonym | Exact | HD | |||
| Huntington disease | |||||
| Huntington's chorea | |||||
| Parent | Is_a | DOID:1289 | |||
| DB_info | Database | OMIM | disease | 143100 | |
| Disease_model_annotation (24) | |||||
| Attribute_of | Gene_by_biology | WBGene00018294 | |||
| WBGene00000474 | |||||
| WBGene00000473 | |||||
| WBGene00018467 | |||||
| Gene_by_orthology (56) | |||||
| Disease_modifier_gene | WBGene00021934 | ||||
| Disease_model_variation | WBVar00092875 | ||||
| Disease_modifier_variation | WBVar00241632 | ||||
| Disease_model_strain (11) | |||||
| Disease_model_transgene | WBTransgene00001975 | ||||
| Disease_model_genotype | WBGenotype00000027 | ||||
| WBGenotype00000068 | |||||
| Molecule_modifier | WBMol:00005124 | ||||
| WBMol:00002745 | |||||
| WBMol:00007948 | |||||
| WBMol:00007949 | |||||
| WBMol:00007970 |
