WormBase Tree Display for Expr_pattern: Expr10033
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| Expr10033 | Expression_of | Gene | WBGene00008018 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00008018 | |||
| Expression_data | Anatomy_term | WBbt:0003679 | Certain | |
| WBbt:0005300 | Certain | |||
| WBbt:0006751 | Certain | |||
| WBbt:0006759 | Certain | |||
| GO_term | GO:0005769 | |||
| GO:0000138 | ||||
| GO:0005797 | ||||
| GO:0005829 | ||||
| Subcellular_localization | Fluorescently labeled TBC-8 showed a cytosolic localization with some punctate membrane staining. Partial localization of TBC-8 was observed with medial (mannosidase II) and trans-Golgi (APT-9) markers and an almost complete co-localization with the early endosomal marker RAB-5. However, we could not observe any localization of TBC-8 to RAB-7-positive late endosomes. This suggests that TBC-8 acts at the Golgi-endosomal interface. | |||
| Type | Reporter_gene | |||
| Pattern | tbc-8 is exclusively expressed in neurons including the head and tail neurons as well as neurons in the ventral nerve cord (VNC). | |||
| Picture | WBPicture0000012737 | |||
| WBPicture0000012738 | ||||
| Reference | WBPaper00041154 | |||
| Transgene | WBTransgene00031340 |
