Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Expr_pattern: Expr10991

expand all nodes | collapse all nodes | view schema

Name Class

Expr10991Expression_ofGeneWBGene00001249
Reflects_endogenous_expression_ofWBGene00001249
Expression_dataLife_stageWBls:0000002
Anatomy_termWBbt:0005300Certain
WBbt:0005403Certain
WBbt:0005753Certain
WBbt:0006912Certain
WBbt:0006917Certain
WBbt:0006918Certain
WBbt:0007846Certain
GO_termGO:0005634
GO:0030424
GO:0043025
TypeReporter_gene
Patternelt-1 reporter gene expression was first seen around the 20-30 cell stage and was maintained during subsequent early embryogenesis in cells corresponding to hypodermal precursor cells. Just prior to morphogenesis, reporter gene expression could be seen in all the major hypodermal cell nuclei. During formation of the comma stage, embryo reporter gene expression declined in the dorsal and ventral hypodermis but remained high in the lateral seam cells. The seam-cell expression of the reporter gene continued throughout morphogenesis to the pretzel stage although at lower levels. In addition, at the threefold stage of development high levels of expression were seen in a group of cells adjacent to the pharynx in a position consistent with neuronal cells of the retrovesicular ganglion. During postembryonic development relatively low levels of expression were maintained in seam cells from the L1 to the adult stage as were high levels of ELT-1 in neuronal cells of the retrovesicular ganglion. ELT-1 expression was also clearly apparent in several different groups of neuronal cell bodies and axons; those of the ventral cord were the most prominent. Expression was also seen in several neurons in which the axon extended from the ventral cord and encircled the pharynx just in front of the posterior bulb.The reporter gene also showed postembryonic expression in sex-specific structures. In hermaphrodites, ELT-1 expression was seen in the vulval muscles (vm1 and vm2) and in males, in a subset of the lateral seam, the SET cells, that give rise to the sensory rays.
ReferenceWBPaper00042315
TransgeneWBTransgene00017257
WBTransgene00018200
WBTransgene00018201