WormBase Tree Display for Expr_pattern: Expr11178
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| Expr11178 | Expression_of | Gene | WBGene00000857 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00000857 | |||
| Expression_data | Anatomy_term | WBbt:0005300 | Certain | |
| WBbt:0005753 | Certain | |||
| WBbt:0005792 | Certain | |||
| WBbt:0005813 | Certain | |||
| WBbt:0005821 | Certain | |||
| Type | Reporter_gene | |||
| Pattern | Expression of cwn-1 Wnt ligand decreases during aging. In very young adult worms, day 1 of adulthood, cwn-1/Wnt is expressed in body-wall muscles and ventral cord motor neurons in the posterior part of the worm. However, cwn-1/Wnt expression in body-wall muscles almost entirely disappears in the following 24 hours. By day 2 of adulthood we were able to observe only cwn-1 expression in ventral cord motor neurons. This expression is low in middle-age (day 5) worms, and barely detectable in old (day 12) animals. Overall the cwn-1/Wnt expression pattern is similar to that previously observed during development. In addition to body-wall muscles and ventral cord motor neurons, cwn- 1/Wnt was detected in intestinal cells, vulval muscle, and fused seam cells during larvae development (Gleason et al. 2006), although this expression pattern is absent in adulthood. | |||
| Reference | WBPaper00043969 | |||
| Transgene | WBTransgene00018840 |
