WormBase Tree Display for Expr_pattern: Expr11357

Expr11357 Expression_of: Gene: WBGene00012341
    Reflects_endogenous_expression_of: WBGene00012341
  Expression_data: Anatomy_term (12)
    GO_term: GO:0005886
      GO:0005737
      GO:0031410
  Subcellular_localization: In many cases, particularly neurons, the fusion protein localizes to cytoplasmic puncta that probably correspond to membranous vesicles. In other tissues, e.g., pharyngeal cells and gonadal sheath cells, CATP-6::GFP is closely associated with the plasma membrane. Most significantly with regard to the effect of catp-6(0) on gonadogenesis, CATP-6::GFP is associated with the plasma membrane of the somatic gonad precursor cells, Z1 and Z4. Although the authors detect CATP-6::GFP in close association with the plasma membrane in some tissues, they cannot certain that the protein is actually located within the plasma membrane. For example, in the case of Z1 and Z4 the fluorescence pattern of CATP-6::GFP (unlike that of GEM-1::GFP) is often discontinuous along the periphery of the cell. Thus, it remains possible that the protein localizes to vesicles that are just beneath the plasma membrane. Furthermore, it is possible that CATP-6 localizes to both plasma membrane and vesicular compartments and that the relative distribution differs between cell types. Higher resolution microscopy will be necessary to resolve this issue.
  Type: Reporter_gene
  Pattern: CATP-6::GFP is expressed in multiple tissues throughout development. These include a) many neurons in the head and tail, b) all body muscles, c) most pharyngeal cells, particularly in the posterior bulb, d) vulval muscles, e) coelomocytes, f) spermatheca, g) gonadal sheath cells, and h) lateral hypodermis.
  Picture: WBPicture0000013513
    WBPicture0000013514
    WBPicture0000013515
    WBPicture0000013516
  Reference: WBPaper00044313
  Transgene: WBTransgene00031473